Authors:
Joshua M. Grolman, Douglas Zhang, Andrew M. Smith, Jeffrey S. Moore, & Kristopher A. Kilian
Summary:
The spatial positioning of 3D tumor-mimetic microenvironments, containing multiple cell types, is controlled with a simple concentric flow device in a single step. A range of geometric architectures are demonstrated, and the migration of segregated tumor cells and macrophages is explored using drugs that inhibit heterotypic interactions.
Source:
Advanced Materials; (08/18/15)