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Blood Analyses May Predict Risk of Delirium in Older Surgical Patients

Markers may help identify patients who would benefit from preventive measures against delirium.

Delirium, or sudden severe confusion due to rapid changes in brain function that can occur with physical or mental illness, affects 15% to 53% of older surgical patients. New research led by investigators at Beth Israel Deaconess Medical Center (BIDMC) may now help clinicians assess an individual patient's risk of developing post-operative delirium, enabling preventive measures to safeguard their health. The research also provides insights into the potential mechanisms involved in the development of delirium, which could lead to new therapeutic strategies.

Delirium in older surgical patients has been linked with longer hospital stays, greater postoperative complications, and higher rates of discharge to nursing homes. In the United States, health care costs attributable to delirium are upwards of $164 billion annually, yet there are no established biological markers to guide the diagnosis or management of the condition.

To look for potential blood-based markers of delirium, a team led by senior investigators Towia Libermann, PhD and Edward Marcantonio, MD, SM, both of BIDMC, screened plasma from adults without dementia aged 70 and older undergoing major non-cardiac surgery using data from the Successful Aging after Elective Surgery Study. Of the 566 patients enrolled, 24 percent experienced delirium. Plasma was collected at four time points: preoperatively (PREOP), in the postanesthesia care unit (PACU), on postoperative day 2 (POD2), and at a 1-month follow-up appointment (PO1MO).

High levels of a protein called C-reactive protein (CRP), which has been linked to inflammation and infection, emerged from an analysis of more than 100 proteins as being strongly linked to delirium. Compared with patients without delirium, those with delirium had significantly higher plasma CRP levels at PREOP, PACU, and POD2, but not at PO1MO.

Although the relationship between CRP and delirium has been previously reported, this study is the first to document and analyze CRP levels before onset of symptoms.

"Our findings demonstrate that, in patients who go on to develop delirium, CRP levels in blood are slightly increased before surgery and further increase after surgery relative to patients who do not develop delirium," said Libermann, who is Director of the Genomics, Proteomics, Bioinformatics and Systems Biology Center at BIDMC and Associate Professor of Medicine at Harvard Medical School (HMS). Further, he noted that increased plasma CRP levels are linked to various clinical conditions, which means that CRP is not a highly specific marker for delirium. To identify more selective delirium markers, the investigators are planning to expand their search to include metabolites, lipids, and less abundant proteins in the blood. "We anticipate that the most specific delirium biomarkers will be found at very low concentrations and not among the most common proteins," Libermann explained.

Uncovering such markers may provide clues regarding the mechanisms that underlie the development of delirium. "We speculate that, despite the heterogeneity of patients and delirium, common mechanisms are shared by all patients developing postoperative delirium and that a pre-inflammatory state as reflected by slightly increased levels of CRP even before surgery predisposes patients to a more pronounced inflammatory response upon surgery that increases the likelihood of delirium," said Libermann.

"From a clinical standpoint, our findings suggest that CRP could be used to risk stratify patients before surgery, enabling proactive interventions that target patients at risk for developing postoperative delirium," said Sarinnapha Vasunilashorn, PhD, co-lead author and postdoctoral fellow in the Division of General Medicine at Primary Care at BIDMC and HMS.

Marcantonio, a board-certified geriatrician who is Section Chief for Research in the Division of General Medicine and Primary Care at BIDMC and Professor of Medicine at HMS, added, "This is a great example of translational research using the combined efforts of a top-notch patient-oriented research team and the innovative laboratory expertise of Dr. Libermann and co-lead author Dr. Simon Dillon to make an important discovery that will ultimately have a positive impact on how we care for patients."

Illustration: US Department of Health and Human Services.

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EurekAlert! (05/06/16)

Science Daily (05/06/16)

Abstract (Biological Psychiatry; 2016.)

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Prashant Kumta and Robert Kormos and CardioSense Receive Funding from Coulter@Pitt TPII Program Dr. Julie Phillippi Receives 5-year, $1.9 Million NIH R01 Award Pitt’s Center for Medical Innovation Awards Round-1 2017 Pilot Funding Computer Models Provide New Understanding of Sickle Cell Disease New Tool to Distinguish Between Viral, Bacterial Infections Newly Discovered Biomarkers May Lead to Promising Diagnostic Tool for Alzheimer's Lutein, Found in Leafy Greens, May Counter Cognitive Aging Creating Self-Recognizing and Self-Regulating Synthetic Materials Wearable Artificial Lung to Deliver Greater Mobility to Patients Ingestible Drug-Delivery Materials May Help Patients Comply with Treatment Regimens New Brain Death Pathway in Alzheimer's Disease Engineers Invent the First Bio-Compatible, Ion Current Battery Genome Editing with CRISPR-Cas9 Prevents Angiogenesis of the Retina Pitt School of Medicine Signs Collaborative Agreement with World-Renowned French Research Institutions Lecture: Dr. Marc Simon, Lead Investigator, Phase 2 Study in Patients with Pulmonary Hypertension Working the [Immune] System NIH Continues Pitt’s Cardiovascular Bioengineering Training Program Nanoscale Forces Measured in Aortic Smooth Muscle Cells Tell Story of Disease Comparing Algorithms That Search for Cancer Mutations New Tools Help Surgeons Find Liver Tumors, Not Nick Blood Vessels Many New Genetic Markers for Lupus Identified in Large Multi-Ethnic Study Toddler Brain Development: Bacterial Clues Found in Dirty Baby Diapers Promising Target to Protect Bone in Patients with Diabetes New Discovery Holds Potential for Treating Tuberculosis Neurodegenerative Diseases: A Biophysical Smoking Gun Traumatic Brain Injury in Veterans: Differences from Civilians May Affect Long-Term Care Tumor-Targeting MRI Contrast Developed, Based on Human Protein Former Badylak Lab Member Now Director of Preclinical Development at PECA Labs, Inc. Brain's Immune Cells May Drive Overeating and Weight Gain Repurposed Asthma Drug Shows Blood Sugar Improvement Among Some Diabetics Connection Between Autophagy and Lifespan: Scientists Take a Deeper Dive into Cellular Trash Personal Neoantigen Vaccine Prompts Strong Anti-Tumor Response in Patients, Study Shows Investigating Folding Stability and Dynamics of Proteins Phase 1 Clinical Trial for the Treatment of Severe Neurological Diseases Begins Earliest Molecular Events Leading to Organ Rejection Identified in Mice University of Pittsburgh’s Patent Record Broken 2 Years in a Row Shining Light on Brain Cells that Coordinate Movement Readily Available Drug Cocktail Can Help Prevent Sepsis Shock and Death New Tool to Identify and Control Neurons Where Are the New Therapies for Heart Disease? Brains Evolved to Need Exercise Insomnia Medication May Wake Up Some Patients from Vegetative State Chatter in the Deep Brain Spurs Empathy in Pre-Clinical Trials DRPs May Improve Cancer-Specific Outcomes in the Liver DNA Sent on Sequential, and Consequential, Building Mission Study Casts Doubt About Link Between Eczema, Cardiovascular Disease Hi-Res View of Protein Complex Shows How It Breaks Up Protein Tangles Gut Bacteria Might One Day Help Slow Down Aging Process New Antibiotic Effective Against Drug-Resistant Bacteria Mutations That Allow Bird Flu Strain to Spread Among Humans Identified Plant Compound More Powerful Than AZT Against HIV Use of Prefabricated Blood Vessels May Revolutionize Root Canals How Blows to the Head Cause Numerous Small Swellings Along the Length of Neuronal Axons Drug Lowers Levels of Biomarker Linked to ALS Study Identifies Potential Biomarker for Alzheimer's Disease Technology Unlocks Mold Genomes for New Drugs Researchers Identify Inhibitor That Overcomes Drug Resistance in Prostate Cancer Cellular Sweet Spot Found in Skin-Cancer Battle Western Diet Increases Alzheimer's Pathology in Genetically Predisposed Mice Animal Models Can't 'Tune Out' Stimuli, Mimicking Sensory Hypersensitivity in Humans New Cancer Drug Tested in Mice May Benefit Certain Leukemia Patients Low Levels of Vitamin A May Fuel TB Risk Key Feature for Modeling How Cells Spread in Fibrous Environments Injured Bones Reconstructed by Gene and Stem Cell Therapies Dr. Stephen Badylak Participates in World Science Festival Journal of Surgical Research Features Work of Dr. William Wagner 1 in 5 Surgical Weight-loss Patients Take Prescription Opioids 7 Years After Surgery Musculoskeletal Transplant Foundation Awards Funding for Novel Craniomaxillofacial Bone Regeneration Project Pitt Professor and Leader of International Sepsis Research Reacts to Global Sepsis Resolution Researchers Discover Mechanism That Controls Bone Formation, Function Remembrance of Things Past: Bacterial Memory of Gut Inflammation Stem Cells Yield Nature's Blueprint for Body's Vasculature Mind-Controlled Device Helps Stroke Patients Retrain Brains to Move Paralyzed Hands Genes Responsible for Severe Congenital Heart Disease Identified by Pitt Researchers Can Omega-3 Help Prevent Alzheimer's Disease? Brain SPECT Imaging Shows Possible Link Antibody for Fighting Cancer Emerges Brain Blood Vessel Lesions Tied to Intestinal Bacteria Blood Discovery Could Benefit Preemies, Help End Platelet Shortages Storing a Memory Involves Distant Parts of the Brain Precision Medicine Improves Treatment Outcomes for Some Pancreatic Cancer Patients Stem-Cell Transplants Show Limited Benefit for Double-Hit Lymphoma Patients in Remission New Gene Identified in Lou Gehrig's Disease New Finding Affecting Immune Reconstitution Related to B Cells Gut Microbiome May Predict Response to Biologic Therapy for Inflammatory Bowel Disease First 'Nanotherapeutics' Delivered to a Tumor New Blood Test Is More Accurate in Predicting Prostate Cancer Risk Than PSA Traumatic Brain Injuries May Be Helped with Drug Used to Treat Bipolar Disorder Kidney Research Leads to Surprising Discovery About How the Heart Forms Poor Overall Environmental Quality Linked to Elevated Cancer Rates Cancer Cells Shown to Co-Opt DNA 'Repair Crew' Modified Insulin and Red Blood Cells Used to Regulate Blood Sugar Neuronal Targets to Restore Movement in Parkinson's Disease Model Platelets Suppress T Cell Immunity Against Cancer Fixing Broken Hearts Through Tissue Engineering Novel Gene Editing Approach to Cancer Treatment Shows Promise in Pre-Clinical Tests New Line of Attack on Spinal Muscular Atrophy Mice with Missing Lipid-Modifying Enzyme Heal Better after Heart Attack Combination Therapy Could Provide New Treatment Option for Ovarian Cancer New Insight into Powerful Inflammatory Regulator A Transplant and a Cure: Research Team Eradicates Hepatitis C in 10 Patients Following Lifesaving Transplants from Infected Donors Bacterial metabolism affects the C. elegans response to cancer chemotherapeutics ALung Submits IDE Application to FDA Seeking Approval to Conduct Pivotal Study of the Hemolung RAS Studying a Catalyst for Blood Cancers Lyme Disease Researchers Seek Consensus as Number of Cases Grows Discovery Offers New Hope to Repair Spinal Cord Injuries Using CRISPR to Reverse Retinitis Pigmentosa and Restore Visual Function Skin Stem Cells Used to Generate New Brain Cells Does the Microbiome Play a Role in the Effectiveness of Colorectal Cancer Treatment? Implanted Scaffold with T Cells Rapidly Shrinks Tumors Protein Primes Mouse Stem Cells to Quickly Repair Injury, Study Finds Motor Neurons Adjust to Control Tasks, New Brain Research Reveals Dr. Anna Balazs to Lead DOD MURI Program Project McGowan Institute Spin-Out Company Closes $36 Million Financing Rapid Screening Machine Can Read and Separate Protein Sequences Cytokine Controls Immune Cells That Trigger Inflammatory Bowel Disease, Study Finds Scientists Combine a Peptide with a Nano Cancer Drug Formulation to Improve Treatment Effectiveness and Prevent Metastasis in Pancreatic Cancer Researchers Successfully Prevent Graft-Versus-Host Disease 2017 Gordon Research Seminar on Elastin, Elastic Fibers & Microfibrils Wheelchair Powered by Compressed Air, Designed by University of Pittsburgh Time-Lapse Video Reveals Cells Essential for 'Birth' of Blood Stem Cells Newfound Signal Helps Pancreatic Cancer Cells Hide from Immune System Pitt-Developed Artificial Lung Shows Promise in Pre-Clinical Trials Blood Vessels and the Immune System Talk to Each Other Screening the Dark Genome for Disease Technology to Screen Embryos Before Implantation Falls Short How Melanoma Tumors Form Stretching the Boundaries of Neural Implants Helping the Retina Regenerate Genetic Errors Associated with Heart Health May Guide Drug Development US Burden of Neurological Disease Is Nearly $800 Billion/Year Physician Judgment as Good as Complex Protocol for Sepsis Finds Seven-Country Collaboration Interaction Among Proteins that Cause Cancer Cells to Metastasize Scientist Pioneers New Technology, Maps Giant Virus Rogue Breast Tumor Proteins Point to Potential Drug Therapies Protein that Regulates Brain Cell Connections Could Be New Target for Treating Alzheimer's Disease Chemists Create Microscopic Environment to Study Cancer Cell Growth Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation NSF Award to Develop Ultrasonic Sensors for a Hybrid Exoskeleton Received Funding to Establish NIDCR Consortium for Tissue Regeneration Therapies Received from NIH Untreated Sleep Apnea in Children Can Harm Brain Cells Tied to Cognition and Mood Osteoporosis Drug Found Safe in Long-Term Trial Researchers Review Progress of Treating Glutamate Signaling in Depression Drosophila Effectively Models Human Genes Responsible for Genetic Kidney Diseases Autism: New Analysis Method of Metabolites Accurately Predicts Whether a Child Has Autism Dietary Anti-Cancer Compound May Work by Influence on Cellular Genetics Genetic Association with Aggressive Prostate Cancer Discovered New Drug Delivery Method for Cancer Therapy Developed Electroacupuncture Releases Stem Cells to Relieve Pain, Promote Tissue Repair, Study Finds Fat Cells Step In to Help Liver During Fasting First Steps in Human DNA Replication Dance Captured at Atomic Resolution Unproven Stem Cell 'Therapy' Blinds Three Patients at Florida Clinic Research Could Lead to Better Vaccines and New Antivirals Molecule Stops Fatal Pediatric Brain Tumor Lack of Oxygen, Not Excessive Stimulation, Cause for Half of Seizure-Related Brain Damage in Epilepsy New Structural Studies Reveal Workings of a Molecular Pump That Ejects Cancer Drugs Decoding the Genome's Cryptic Language Novel 'Barcode' Tracking of T Cells in Immunotherapy Patients Identifies Likely Cancer-Killers Antibiotics Used to Treat Cystic Fibrosis Increases Risk of Permanent Hearing Loss Diamonds That Deliver Dietary Prebiotics Improve Sleep, Buffer Impacts of Stress, Says Study McGowan Institute for Regenerative Medicine Holds Its Annual Scientific Retreat Catalytic Conveyor Belt Study Shows Strong Long-Term Survival Rates for Patients with GIST From Mice, Clues to Microbiome's Influence on Metabolic Disease Low Level Vitamin D During Remission Contributes to Relapse in Ulcerative Colitis Patients Second Cause of Hidden Hearing Loss Identified Immune Cell Serves As an Essential Communications Link for Migrating Cells Vitamin B3 Prevents Glaucoma in Laboratory Mice Scientists Monitor Crosstalk Between Intestinal Microbes and Immune System Food Additive Found in Candy, Gum Could Alter Digestive Cell Structure and Function Regenerative Medicine for Whole Organ Replacement Meditation and Mindfulness Practices: Heart Patient’s Treatment Plan Options Luminescence Switchable Carbon Nanodots Follow Intracellular Trafficking and Drug Delivery Understanding Enzymes: New Tool Can Help Researchers Identify Enzymes, and Their Abundance, in Microbiomes Neurons Support Cancer Growth Throughout the Body 'Achilles' Heel' of Key Anti-Cancer Protein Drug Could Prevent Infertility in Cancer Patients Cellular Quality Control Process Could Be Huntington's Disease Drug Target Routinely Prescribed Antibiotic May Not Be Best for Treating Severe C. Diff Infections Atomic-Scale View of Bacterial Proteins Offers Path to New Tuberculosis Drugs Cancer Drug Could Promote Regeneration of Heart Tissue Missing Link for Fighting Viral Pneumonia Identified Unhealthy Gut Microbes a Cause of Hypertension, Researchers Find Gene Therapy Restores Hearing in Deaf Mice, Down to a Whisper Molecular Medicine Features Work of McGowan Institute Affiliated Faculty Members Stem Cell Secretions May Protect Against Glaucoma Artificial Intelligence Uncovers New Insight into Biophysics of Cancer Research Suggests Way to Improve Stroke Treatments Examining Women's Bones During Menopause May Help Head Off Fractures Medical Milestone: 2000 Lung Transplants Microscopic Submarines for Your Stomach New Treatment Recommendations for a High-Risk Pediatric Leukemia Scientists Get Best View Yet of Cancer-Causing Virus HPV Noninvasive Ultrasound Pulses Used to Precisely Tweak Rat Brain Activity Nutritional Considerations for Healthy Aging, Reduction in Age-Related Chronic Disease Cervical Cancer Mortality Rates May Be Underestimated Scientists Reprogram Embryonic Stem Cells to Expand Their Potential Cell Fates Markers for Prostate Cancer Death Can Identify Men in Need of More Aggressive Treatment Melanoma Mutation Likes Fat for Fuel Scientists Identify Protein Central to Immune Response Against Tuberculosis Bacteria New Technology Enables 5-D Imaging in Live Animals, Humans Pitt’s Center for Medical Innovation Awards Four Novel Biomedical Devices Award: Ambulatory Assist Lung for Children Study Finds Patterns of Biomarkers Predict How Well People Age, Risks of Age-Related Disease Study Characterizes Key Molecular Tool in DNA Repair Enzymes Brain Protein Predicts Recovery Time Following Concussion Halting Lethal Childhood Leukemia Researchers Find Key Genetic Driver for Rare Type of Triple-Negative Breast Cancer Tailored Organoid May Help Unravel Immune Response Mystery University of Pittsburgh Cancer Institute Academy Expands Summer Scholar Program to Include College Students New Stem Cell Delivery Approach Regenerates Dental Pulp-Like Tissue in a Rodent Model DNA Markers Distinguish Between Harmless, Deadly Bacteria Long-Term Anti-Inflammatory Drug Use May Increase Cancer-Related Deaths for Certain Patients First Use of Graphene to Detect Cancer Cells Nanoparticle-Based Method Shows Promise in DNA Vaccine Delivery Discoveries from Largest Genome-Wide Study of Chronic Liver Disease Ancient Chinese Malaria Remedy Fights TB Oral Vaccine Against Salmonella Developed Understanding Why We Should Exercise New Study Shows Targeted Therapy Needed for Breast Cancer with Brain Metastases Researchers Find Bacterial Protein That Boosts Insulin-Producing Cells in Zebrafish Aging Process Increases DNA Mutations in Important Type of Stem Cell Loss of ARID1A Protein Drives Onset, Progress of Colon Cancer Cholesterol-Fighting Drugs Lower Risk of Alzheimer's Disease Mystery Molecule Is a Key to Inhibiting Colon Cancer Rare Obesity Syndrome Therapeutic Target Identified Bacterial 'Sabotage' Handicaps Ability to Resolve Devastating Lung Inflammation in Cystic Fibrosis Breast Cancer Update: Sentinel Node Biopsy Guidelines Encourage 'Less Is More' Approach How Do You Mend a Broken Heart? International Team Decodes Cellular Death Signals Tailoring of Protein Stability and Performance via Polymer-Based Protein Engineering Pitt Researchers Collaborate to Develop Lifesaving "Rescue Stent" Cancer Cells Hijack DNA Repair Networks to Stay Alive, Pitt Study Shows Preclinical Study: Using MRI to Monitor ECM Hydrogel in the Brain Post-Stroke Pitt to Lead Trauma Network, Up to $90M in Department of Defense-Funded Trauma Research Balancing Time and Space in the Brain: A New Model Holds Promise for Predicting Brain Dynamics Topical Therapy for Radiation-Induced Skin Damage Shows Promising Results $2.95 Million NIH Grant to Predict At-Risk Cerebral Aneurysms Received Pitt Researcher Part of Team That Discovered Way to Induce Visual Hallucinations Brown Lab Students Take 2nd Place in Michael G. Wells Student Healthcare Entrepreneurship Competition Concussions are Treatable, More Research Needed In a First, Pitt-UPMC Team Helps Paralyzed Man Feel Again Through a Mind-Controlled Robotic Arm Pitt-UPMC Neurosurgeon to Lead BRAIN Initiative Grant to Study How We Speak New Territory Analyzing DNA Modifications in Glioblastoma Young Blood Does Not Reverse Aging in Old Mice Investigators Pinpoint Cause, Possible Treatment for Rare Form of Sarcoma Structure of Human Astrovirus Could Lead to Antiviral Therapies, Vaccines History of Cells Told Through MEMOIR Antihypertensive Medications and Fracture Risk: Is There an Association? Plant Compounds May Boost Brain Function in Older Adults, Study Says Expression of Specific Gene Differentiates Moles from Melanoma New Topical Immunotherapy Effective Against Early Skin Cancer Common Probiotics Can Reduce Stress Levels, Lessen Anxiety Pitt Researchers Uncover Key Mechanisms of Cancer, Aging, and Inflammation Brain Needs to Be Retrained After ACL Injury Study Challenges Model of Alzheimer's Disease Progression Weight Loss After Obesity Doesn’t Cut Risk of Certain Types of Cancer Research Connects First-Time Kidney Stone Formers and Chronic Kidney Disease Two Distinct Genetic Subtypes Found in Crohn's Disease Patients Regeneration of Spinal Nerve Cells Boosted New Non-Invasive Assay May Improve Surveillance of Heart and Other Solid-Organ Transplants New Molecule May Help Fight Obesity by Converting 'Bad' Fat to 'Good' Fat New Model for Understanding Myeloma Imaging with New Biomarker Tracks Tumor Progression, Response to Treatment for Common Brain Cancer Hypothyroidism Symptoms Linger Despite Medication Use, Normal Blood Tests Genome Engineering Paves Way for Sickle Cell Cure Dysfunction in Neuronal Transport Mechanism Linked to Alzheimer's Disease Common Prostate Cancer Treatment Linked to Later Dementia, Researcher Says Common Nerve Protein Elevated in Aggressive Neuroblastomas Calcium Supplements May Damage the Heart Mars-Bound Astronauts Face Chronic Dementia Risk from Galactic Cosmic Ray Exposure Brain Modulyzer Provides Interactive Window into the Brain New Study Finds 'Amplifier' Helps Make Connections in the Fetal Brain Major Racial Bias Found in Leading Genomics Databases Vaccinating Babies Without Vaccinating Babies Not Really a Matter of Choice? Acute infectious gastroenteritis potentiates a Crohn's disease pathobiont to fuel ongoing inflammation in the post-infectious period Grant Received from Hillman Foundation to Advance Brain Research Pitt Scientists Identify How Repair Protein Finds DNA Damage World-Renowned Expert in Research and Therapies for Blindness and Vision Impairment Joins McGowan Institute Preclinical Research: Potential Treatment of IBD Different Brain Atrophy Patterns May Explain Variability in Alzheimer’s Disease Symptoms Link Between Heart and Blood Cells in Early Development New Tool for Cancer Patients Measures the Stress of Expenses What's Really Going On in PTSD Brains? Experts Suggest New Theory Mystery of Bacteria's Antibiotic Resistance Unraveled Human Neurons Continue to Migrate After Birth Preliminary Zika Vaccines Prevent Neurological Disorders in Newborn Mice Pitt Team Receives $2.5 million in DOD Funds for First Retrievable Vascular Stent Wave of the Future: Micro Swimming Drone to Traverse the Human Body Using Sound Waves Researchers Receive NIH Grant to Develop Better Methodology to Treat Rotator Cuff Tears Abnormal Brain Protein May Contribute to Alzheimer's Disease Development Giant Thai Insect Reveals Clues to Human Heart Disease Key Players Responsible for Learning and Memory Formation Uncovered What Happens When the Brain Is Artificially Stimulated? Pediatric Atopic Dermatitis May Benefit from Early Immune Intervention Tattoo Therapy Could Ease Chronic Disease Immune and Targeted Therapies with Radiation Therapy Improves Outcomes for Melanoma Brain Metastases Patients, Say Researchers Fungus in Humans Identified for First Time as Key Factor in Crohn's Disease Activity Trackers Are Ineffective at Sustaining Weight Loss Stem Cells Grown into 3-D Lung-In-A-Dish Can Sertraline Prevent Depressive Disorders Following Traumatic Brain Injury? Molecular Switch Controlling Immune Suppression May Help Turn Up Immunotherapies Rare Genetic Condition May Provide Insights on Parkinson’s and Other Late-Onset Diseases Abaloparatide Benefits a Wide Range of Postmenopausal Women with Osteoporosis Gut Pathogens Thrive on Body's Tissue-Repair Mechanism Industry/Pitt Partnership to Advance Additive Manufacturing Problem-Solving for Industry How Ionizing Radiation Damages DNA and Causes Cancer Case for Liquid Biopsies Builds in Advanced Lung Cancer Researchers Identify New Therapeutic Target for Cancer Six-Day Clinical Trial Finds Integrative Medicine Program Alters Blood Serum New Software Helps to Identify Course of Cancer Metastasis, Tumor 'Evolution' Using Light to Image and Potentially to Treat PTSD NIH Funds Research Project Cooperative Agreement “Materials That Compute” Advances as Engineers Demonstrate System Performs Pattern Recognition New HIF-2 Kidney Cancer Therapy More Effective than Current Treatment, Study Shows Biochemists' Discovery Could Lead to Vaccine Against 'Flesh-Eating' Bacteria 3-D Graphene Has Promise for Bio Applications Making Memories Stronger and More Precise During Aging Gene Therapy via Ultrasound Could Offer New Tool in Fight Against Heart Disease and Cancer New Understanding of Pulmonary Hypertension Leads to Promising Drug Targets Telemedicine Could Improve Eye Exam Access for People with Diabetes Probing How CRISPR-Cas9 Works Shifts in the Microbiome Impact Tissue Repair, Regeneration Sertraline, Brand Named Zoloft, Improves Functioning in Young Children with Fragile X Doctors Prescribe Diabetes Treatment Medications 15 Times More than Obesity Drugs Looking To Saliva to Gain Insight on Evolution Scientists Uncover Common Cell Signaling Pathway Awry in Some Types of Autism Flesh-Eating Infections in Rheumatoid Arthritis Patients Spur New Discovery Increased Eye Cancer Risk Linked to Pigmentation Genes That Dictate Eye Color MRI Technology Quantifies Liver Response in Nonalcoholic Steatohepatitis Patients Refining Optogenetic Methods to Map Synaptic Connections in the Brain Researchers Find Herpes Strain in the Nervous System Electrical Synapses in the Brain Offer New Avenue for Epilepsy Research and Possible Treatment Correcting Metabolic Deficiencies May Improve Depression Symptoms New Study Reveals a Novel Protein Linked to Type 2 Diabetes How Mechanical Force Triggers Blood Clotting at the Molecular Scale CRISPR Gene Editing Reveals New Therapeutic Approach for Blood Disorders Expanded Role of PARP Proteins Opens the Door to Explore Therapeutic Targets in Cancer Pulmonary Complications in Adult Survivors of Childhood Cancer Directly Reprogramming a Cell's Identity with Gene Editing 'Bursts' of Chromosome Changes Fuel Breast Cancer Tumor Growth University of Pittsburgh Licenses Novel Microneedle Patch to Pittsburgh Company From Sci Fi to Reality: Unlocking the Secret to Growing New Limbs Scientists Identify Marker for Myeloid-Derived Suppressor Cells Discovery of Infants' Airway Microbiomes May Help Predict Lung Disease Vision: When It Comes To Recognizing Shapes, Timing Is Everything How Epigenetics Regulate Vital Functions from Bacteria to Humans New Tool Enables Researchers to Rapidly Manipulate Protein Levels in Mammalian Cells Pitt Researchers Solve Mystery on How Regenerative Medicine Works ‘Starving’ Immune Cell Discovery Points to Cancer Immunotherapy-Boosting Strategies Sampling Method Used for New Breast Cancer Tests May Lead to Underestimate of Risk NIH-Funded Pitt Research Study to Evaluate New Voice Therapy Technique More Doesn’t Mean Better When it Comes to Trauma Centers Biotech Firm Licensing Pitt Patents Raises $57M Cumulative Risk for Relatively Safe Medication Like Statins Is Nontrivial Mice Survive Brain Cancer Tumors Lacking Key Surface Proteins Novel Compounds Arrested Epilepsy Development in Mice Ecologists Create a Framework for Predicting New Infectious Diseases Research Offers New Hope for Understanding Deadly Infections Researchers ID Cancer Gene-Drug Combinations Ripe for Precision Medicine Neural Networks: Why Larger Brains Are More Susceptible to Mental Illnesses Plant Compounds Give '1-2' Punch to Colon Cancer Researchers Temporarily Turn Off Brain Area to Better Understand Function Regenerative Medicine Improves Strength and Function in Severe Muscle Injuries Drs. Weinbaum, Kameneva, and Waters Receive CMI Grants New Fully Dissolving Heart Stent Biochemists Feed 'Poison Pill' to Deadly Virus Key to Regulating Cell's Powerhouse Discovered Local Drug Activation at Solid Tumor Sites Alzheimer's Gene May Show Effects on Brain Starting in Childhood Heart Failure After First Heart Attack May Increase Cancer Risk Extra-Coding RNAs Regulate DNA Methylation in the Adult Brain Mitochondria Are Exploited in Cancer for Tumor Cell Motility, Metastatic Competence HIV Study Confirms Clinically Viable Vaccine Paving the Way for Future Treatments Two Groundbreaking Studies Reflect New Paradigm in Breast Cancer Research Drs. Robert Parker and Gilles Clermont Receive NIH R21 Award Fabrication of Vascular Grafts with Artificial Stem Cells Gene Mutation 'Hotspots' Linked to Better Breast Cancer Outcomes New Technology Helps ID Aggressive Early Breast Cancer Tracking Brain Atrophy in MS Could Become Routine, Thanks to New Software Treating Autoimmune Disease Without Harming Normal Immunity A Little Spark for Sharper Sight Zika Virus Identified in Brain, Placenta Tissue, Strengthening Link to Birth Defects Broccoli Sprout Extract May Protect Against Oral Cancer Recurrence Incidence of Cancer in Patients with Large Colorectal Polyps Lower Than Previously Thought Dr. Rocky Tuan Receives Research Award to Conduct Studies on International Space Station Pitt Researchers Find Key to Parkinson’s Disease Neurodegeneration Stanford and Pitt Collaborate on Successful Stroke Therapy Device for Irregular Heartbeat May Be More Cost-Effective Than Medication Extent of Resection Associated with Likelihood of Survival in Glioblastoma A Single Species of Gut Bacteria Can Reverse Autism-Related Social Behavior in Mice Future Treatment Strategies for Stomach Ulcers, Inflammatory Bowel Disease, and Alcoholic Liver Disease Shorter Radiation Course Recommended for Early-Stage Breast Cancer Patients Bioactive Film Improves How Implants Bond with Bone in Animal Study Impact of Antibiotic Treatment on Infant Gut Microbiome Revealed Engineering the Immune System to Kill Cancer Cells Super-Resolution Microscopy Reveals Unprecedented Detail of Immune Cells' Surface Researchers Find Potential Key to Preventing Heart Attacks, Strokes in Older Adults Pre- and Post-Testing Show Reversal of Memory Loss from Alzheimer's Disease in 10 Patients Simulations Describe HIV's 'Diabolical Delivery Device' DNA in 'Unbiased' Model Curls Both Ways Lifestyle Optimization to Prevent Disease Facial Reconstruction with Fat Grafting Chemical 'Sponges' Designed to Soak Up Toxic Cancer-Fighting Drugs After Targeting Tumors Swapping Sick for Healthy Brain Cells Slows Huntington's Disease Study Questions Cancer Link with Bone Growth Factor for Spinal Surgery Benefits to Timing Chemotherapy to Body's 'Awake' Time Stress-Diabetes Link Detailed in New Study Scientists Develop Protein with Potential to Modify Brain Function, Memory in Mice and Fish UPMC Researchers Shine Light on Common Heart Complication After Lung Transplantation 3D Bioprinted Model for the Study of Precancerous Breast Disease Aims to Reduce Unnecessary Treatment Dr. Chien Ho Develops Bio-Mimicry Method for Preparing and Labeling Stem Cells Study Finds That Protein Puts the Brakes on Melanin Restoring Chemotherapy Sensitivity by Boosting microRNA Levels Vitamin Nicotinamide Riboside Protects Mice from Diabetes Complications Zika Virus Infects Human Placental Macrophages First-of-Its-Kind Procedure Combines Scalp, Skull, Kidney, and Pancreas Transplant Fasting-Like Diet Reduces Multiple Sclerosis Symptoms Early-Life Stress Causes Digestive Problems and Anxiety in Rats New Study Uncovers Mechanisms Underlying How Diabetes Damages the Heart New Malaria Drugs Kill Plasmodium Parasites by Promoting Premature Parasite Division How Prions Kill Neurons: New Culture System Shows Early Toxicity to Dendritic Spines NSF Grant: Develop a Transistor Based on 2D Crystals to Lower the Energy Consumption of Electronics NIH Grant to Support Continuation of Joint Regenerative Medicine Program Between University of Pittsburgh and Carnegie Mellon University Received Sitting Too Long? Best Stretches for Your Back Flawed Data Behind Regulation of High-Risk Women's Health Devices Immune Cells Help Reverse Chemotherapy Resistance in Ovarian Cancer Lowering Blood Pressure Reduces Risk of Heart Disease in Older Adults Triple-Therapy Cocktail Shrinks Triple-Negative Breast Tumors Can a Healthy Lifestyle Prevent Cancer? Visual Impairment, Blindness Cases in US Expected to Double by 2050 3-D Bioprinted Placenta Could Lead to New Treatments for Preeclampsia Team Discovers New HIV Vaccine Target Gene Regulatory Mutation Linked to Rare Childhood Cancer Diabetes Drug Found No Better Than Placebo at Treating Nonalcoholic Fatty Liver Disease Size of Brain Region Is Associated with Response to PTSD Treatment Voice of America Features Trilogy of McGowan Institute Research Programs Bioengineered Blood Vessel Is Safe for Dialysis Patients, Study Finds Genetic Biomarker May Predict Nerve Pain Side Effects Associated with Prostate Cancer Treatment Repetitive, Subconcussive Head Impacts from Football Associated with Short-Term Changes in Eye Function Omega-3 Lowers Childhood Aggression in Short Term Scientists Find What Might Be Responsible for Slow Heart Function under General Anesthesia Pitt-Developed Drug Works Against ‘Superbug’ Biofilms and Respiratory Virus New Treatment for Children with Acute Respiratory Distress Syndrome No Longer Lost in Translation: Biochemists Watch Gene Expression in Real Time T Cells Use 'Handshakes' to Sort Friends from Foes Gene Linked to Alzheimer's Disease Impairs Memory by Disrupting Brain's 'Playback System' Drs. Rory Cooper and Dan Ding Receive Pitt Chancellor’s Innovation Commercialization Funds Drug-Like Peptides Show Promise in Treating Two Blood Diseases Mothers' Excess Pregnancy Weight Gain, Elevated Blood Sugar 'Imprint' Obesity in Children Blood Analyses May Predict Risk of Delirium in Older Surgical Patients Zika Virus May Cause Microcephaly by Hijacking Human Immune Molecule Quick Test for Zika Effectively Detects Virus in Monkeys Scientists Put Some Muscle Behind Their Research Rapid-Response Immune Cells Are Fully Prepared Before Invasion Strikes Climate Change May Contribute to Rising Rates of Chronic Kidney Disease Genetic Variants in Patients with Crohn's Disease Prevent 'Good' Gut Bacteria from Working Portable Device Worn on Eyeglasses Offers Hope for People with Low Vision Animal Study Shows Flexible, Dissolvable Silicon Device Promising for Brain Monitoring Researchers Track Critical Development in the Young Brain Research Grant Received: Use of Cells from Patient’s Own Fat as Vascular Grafts in Arterial Bypass Surgery Dr. Joon Sup Lee: Advancements in Cholesterol Control Help Move Cardiology Forward Study Pinpoints Mechanism That Allows Cells with Faulty DNA to Reproduce Cell Transplant Treats Parkinson's in Mice Under Control of Designer Drug Study Identifies a Key to Bone Formation, Vertebrate Evolution Four New Genetic Diseases Defined Within Schizophrenia Age-Dependent Changes in Pancreatic Function Related to Diabetes Identified Study Links Residential Radon Exposure to Hematologic Cancers in Women TJP1 Protein May Identify Multiple Myeloma Patients Most Likely to Benefit from Proteasome Inhibitors Scientists Predict Cell Changes That Affect Breast Cancer Growth RNA Splicing Mutations Play Major Role in Genetic Variation and Disease How Cancer Cells Escape From Tumors, Spread Risk Factors Associated with Injurious Falls in the Elderly COPD Linked to Increased Bacterial Invasion Shape of Tumor May Affect Whether Cells Can Metastasize Even a Little Air Pollution May Have Long-Term Health Effects on Developing Fetus How Breast Cancer Cells Slide to Metastasis Study on Fragile X Syndrome Uses Fruitfly's Point of View to Identify New Treatments Minimally Invasive Colitis Screening Using Infrared Technology Could Offer Fast, Simple Test Scientists Reveal Secrets of a Deadly Virus Family Quick Mapping of Our Microbiomes and Metabolomes Cholesterol Levels, Not Statins, Influence Colorectal Cancer Risk Vessel Damage May Precede Diabetic Retinopathy, Researchers Find Scientists Teaching Machines to Make Clinical Trials More Successful Technique Measures 'Postural Sway' to Diagnose Neuromuscular Disorders Pre-Surgical Exposure to Blue Light Reduces Organ Damage in Mice McGowan Institute Technology for Organ and Tissue Preservation Is TechConnect 2016 Award Winner In Child Heart Patients, Novel Approach Improves Symptoms of Hazardous Lymph Blockage Scientists Harness Nature's Transport System to Brain Researchers Develop Magnifying Smartphone Screen App for Visually Impaired Zinc Deficiency May Contribute to Increased Inflammation Among HIV-Positive Individuals Genes That Control Smooth Muscle Contraction Identified Cell Death Mechanism May, Paradoxically, Enable Aggressive Pancreatic Cells to Live On Sophisticated 'Mini-Brains' Add to Evidence of Zika's Toll on Fetal Cortex How Skeletal Stem Cells Form the Blueprint of the Face Dr. Steffi Oesterreich Joins Susan G. Komen As Advisor, New Komen Scholar Dr. Paul Monga to Lead New Multidisciplinary Liver Center Paper Wins International Dupuytren Award 2016 Researchers Identify Potent Antibodies Against HIV Genetic Elements that Drive Regeneration Uncovered Researchers Visualize Brain's Serotonin Pump, Provide Blueprint for New, More Effective SSRIs Much Longer Survival for Heart Transplants Across Species Brain Guardians Remove Dying Neurons Novel 3-D Imaging Offers New Tool for Identifying Advanced Fibrosis in Liver Certain Gastrointestinal Tumors Associated with Higher Mortality Controlling Cell Turnover in the Intestinal Lining Exome Sequencing Improves Doctors' Ability to Diagnose Hard-To-Pin-Down Neurogenetic Disorders Most Patients Likely to See Reductions in Pain and Disability after Bariatric Surgery; Study Identifies Who Benefits Most Seeing Cell To Cell Differences for First Time Explains Symptoms of Rare Genetic Disorders Applying Parameter Selection, Verification Techniques to an HIV Model Researchers Tackle Mystery of Protein Folding Prostate-Specific Antigen Screening Publications Influence Biopsy Rates, Associated Complications Proteins Associated with Schizophrenia Hang Around Longer than Previously Thought Improved Patient Outcomes Linked to Specific Health IT Resources in Hospitals Scientists Issue Report on Advances in Basal Cell Carcinoma Therapy 'Cancer Gene' Twice as Likely to Be Defective in Children with Autism Brain Cancer: Two Essential Amino Acids Might Hold Key to Better Outcomes New Cardiovascular Device That Reduces Risk of Stroke Study of Enzymatic Chemical Reactions by Pitt and Penn State Researchers May Indicate How the First Cells Formed Colonies ECM May Treat Stroke Patients Wnt Secretion Preventing Drugs May Reduce Renal Fibrosis, Study Shows Looking at the Bacteria Inside: New Method of Viewing TB Bacteria Sequence Features Accurately Predict Genome-Wide Mecp2 Binding In Vivo Genetic Changes That Cause Autism Are More Diverse Than Previously Thought Presence of Hormone at Key Developmental Period May Point to Origin of Type 2 Diabetes in Kids Microneedle Patch Delivers Localized Cancer Immunotherapy to Melanoma Curcumin May Help Overcome Drug-Resistant Tuberculosis Unraveling the Mystery of Stem Cells Live-Imaging Technique for Mice Seen as Boost to Studies of Brain Function, Development Neuron Type-Specific Gene Loss Linked to Angelman Syndrome Seizures Dr. Peter Rubin Receives Pittsburgh Health Data Alliance Project Funding Nutrition and Surgical Site Infections: Study New Gene Identified as Cause, Early Indicator of Breast Cancer Study Sheds Light on Patterns Behind Brain, Heart Systems; Circadian Rhythms Why Are Women More Prone to Knee Injuries Than Men? New Technique for Imaging Cells, Tissues Under the Skin Single Brain Cells Reveal Genes Controlling Formation, Development Bariatric Surgery Better Than Intensive Lifestyle, Drug Interventions at Reversing Diabetes in Mildly to Moderately Obese Patients Subset of E. coli Bacteria Linked to Deadly Disease in Pre-Term Infants Women with Impaired Stress Hormone Before Pregnancy Have Lower-Birthweight Babies Future Brain Therapies for Parkinson's Possible with Stem Cell Bioengineering Innovation Imbalance Between Gut Microorganisms, Immune Cells Could Set Stage for Autoimmune Disease Study Shows Spinal Cord Stimulation Reduces Emotional Aspect of Chronic Pain Chemists Develop an Ultra-Sensitive Test for Cancers, HIV Dr. Fabrisia Ambrosio Nets Two NIH Awards FDA: In Silico Trials for Advancing New Devices and Drug Therapy Applications Change in Mosquito Mating May Control Zika Virus Newly Identified Immunity Pathway Protects Mammals from Virus-Caused Cancer Can Nutritional Supplements Impact Genetic Hearing Loss in Children? The Dangers, Risks of Binge Drinking Burning More Calories Associated with Greater Gray Matter Volume in Brain, Reduced Alzheimer’s Risk Researchers Develop Promising Candidate for Next-Generation Anti-Malarial Drug Virus Depends on a Micro-RNA to Replicate Normal Stem Cells Linked to Aggressive Prostate Cancer Research on Treatments for Advanced Ovarian Cancer Predictive Proteins: Elevated Levels Trigger Metastatic Progression of Cancer Cells Molecular 'Brake' Prevents Excessive Inflammation Cooling Technique Protects Speech During Brain Surgery Bariatric Surgery May Reduce Life-Threatening Heart Failure Exacerbation in Obese Patients Discovery of Key Abnormality Affecting Brain Development in People with Down Syndrome Enzymatic Engines Gene Therapy for Parkinson’s Disease to Be Tested by Pitt, UPMC Experts Redefining Sepsis: An International Effort to Improve Patient Outcomes Local Start-Up Based on McGowan Institute Technology Prepares for 2017 US Clinical Trials A Retinal Prosthesis for the Blind Moving Around More Linked to Longer Life Chagas Disease: A Wake-Up Call to Accelerate the Diagnosis, Treatment, and Research Source of Cells Used to Generate New Tissue May Be Important to Personalized Medicine Experimental Ebola Antibody Protects Monkeys Potential Diagnostic for Dengue Fever Outcomes Based on Metabolomic Profiles Only a Small Portion of Synapses May Be Active During Neurotransmission, Study Finds Scientists Prove Feasibility of 'Printing' Replacement Tissue Corneacopia New Study Shows Promise of ALung’s Hemolung Technology to Help Protect the Injured Lung Preventive Surgery for Women at High Risk of Breast, Ovarian Cancer Drug Prevents Key Age-Related Brain Change in Rats 'Gene Fusion' Mutation Uses Three-Way Mechanism to Drive Childhood Brain Cancers The Future of Medicine Could Be Found in This Tiny Crystal Ball Energy from Cellphone Towers Amplify Pain in Amputees It's All About the Timing: Fetal Expression of Core Clock Gene Determines Lifespan in Mice Novel Nanoparticle Made of Common Mineral May Help Keep Tumor Growth at Bay Enzyme Key to Link Between Age-Related Inflammation and Cancer Study Identifies Mechanism for Drug Target to Help Block HIV's Ability to Spread New Light Shed on Anti-Adhesive Molecule in the Vascular Endothelium Sharpin Emerges From the Pack as a Regulator of Inflammation New Drug Target for Rett Syndrome Collagen, Heparan Sulfate Coatings Alter Cell Proliferation, Attachment What Goes Wrong in the Brain When Someone Can't Spell Fabricating Devices for the Detection and Separation of Target Molecules from Complex Fluids DBS: Treating Movement Disorders Delivering Genes Across the Blood-Brain Barrier First Topical Treatment for Common Benign Skin Lesions Discovered: How to Unlock Inaccessible Genes Scientists Discover Protein's Starring Role in Genome Stability, and Possibly Cancer Prevention New Therapy Halts Progression of Lou Gehrig's Disease in Mice Protein Combination Improves Bone Regeneration, Study Shows Scientists Decode Brain Signals Nearly at Speed of Perception Chemists Uncover How Key Agent Allows Diseases to Reproduce Treating Parkinson's Disease by Solving the Mysteries of Movement Food Additive that May Prevent Skin Cancer Revealed by Scientists Promising Results from Clinical Study Using Plasmid DNA Gene Therapy Clinical Milestone Reached with 500 Minimally Invasive Heart Valve Repairs Gene Therapy for Rare Bleeding Disorder Achieves Proof-of-Concept Closer Look at Heart Cell Connectors Could Catch 'Hidden' Rhythm Disorders in the Future Immunity Genes Could Protect Some from E. Coli While Others Fall Ill Using Electrical Signals to Train the Heart's Muscle Cells Slow Heart Rate Does Not Increase Risk of Heart Disease Infant-Friendly Flu Vaccine Developed with Key Protein Genetics Influences Knee Pain Sensitivity in Osteoarthritis Patients Tiny Electronic Implants Monitor Brain Injury, Then Melt Away Link Between Obesity, Increased Risk of Colorectal Cancer Revealed Breast Cancer Study Suggests New Potential Drug Targets and Combinations Versatile New Way to Build Molecules Developed Flexible Film May Lead to Phone-Sized Cancer Detector Key Pathway Involved in Blood Vessel Occlusion Discovered Signals That Make Early Stem Cells Identified Low Blood Levels of Bicarbonate Linked to Earlier Death in Healthy Older Adults What You Eat Can Influence How You Sleep Trio of Autism-Linked Molecules Orchestrate Neuron Connections How the Cell's Power Station Survives Attacks Researchers Kill Drug-Resistant Lung Cancer with 50 Times Less Chemo How Bacterial Communication 'Goes With the Flow' in Causing Infection, Blockage Sedentary Behavior Linked to Poor Health in Adults with Severe Obesity, Independent of Exercise Unraveling the Genetics of Pregnancy and Heart Failure Kidney Injury Common Following Vascular Surgery Simple Shell of Plant Virus Sparks Immune Response Against Cancer Toxic Secretions from Intracranial Tumor Damage the Inner Ear Not Enough YAP Means Too Much Deadly Inflammation Inside the Brain Research Links Inorganic Mercury Exposure to Damaged Cell Processes Nature's Masonry: First Steps in How Thin Protein Sheets Form Polyhedral Shells Absence of Serotonin Alters Development, Function of Brain Circuits Study Uncovers Inherited Genetic Susceptibility Across 12 Cancer Types Vitamin D Levels Linked to Weight-Loss Surgery Outcomes Medical First: Discovery of Warning Symptoms for Usually Fatal Heart Rhythm Malfunction Vitamin A Quells Severity of Preemie Gastrointestinal Disease in Mice Simple Physical Mechanism for Assembly and Disassembly of Structures Inside Cells Stroke Recovery in Mice Improved by Ambien, Study Shows Researchers Identify Potential Approach to Treat Heart Disease Through the Gut Experimental Drugs That Change Energy Supply in Cells Could Slow Brain Tumor Growth Liver Protein Boosts Growth of Insulin-Producing Cells Bones of Obese Children May Be in Trouble ‘Dry Eye’ Linked to Chronic Pain Syndromes Suicide Gene Therapy Kills Prostate Tumor Cells Neural Stimulation Offers Treatment for 'Dry Eye' ASU-Led Researchers Add New Worldwide Resource to Explore Genes' Deep and Hidden Messages Researchers Report Possibility of Using Unused Human Pancreata to Build New Organs Scientists Show How Drug Molecules Regulate a Medically Important Protein Brain Function: First Look at How Astrocytes Function in Humans Recently Approved Heart Drug Poses Potential Risk to Brain and Eye, Researcher Warns Functional Biomarker for Age-Related Macular Degeneration UF Health Researchers Use Gene Therapy to Extend Estrogen's Protective Effects on Memory Combining Adult Stem Cells with Hormone May Speed Bone Fracture Healing A New Way to Deliver MicroRNAs for Cancer Treatment New Method to Calculate Lifetime Energy Requirements of Cells, Genes Nanocarriers May Carry New Hope for Brain Cancer Therapy Scientists Identify Mechanism That May Help Prostate Cancer Cells Escape Effects of Cancer Drugs Ranibizumab Found Effective Against Diabetic Retinopathy Impact of High-Fat Diet on Red Blood Cells May Cause Cardiovascular Disease Molecular Mechanism at Root of Familial Amyloidosis and Other Diseases Grabbing a Parasite by the Tail: Team Solves 'Jumping Gene' Mystery Batten Disease May Benefit From Gene Therapy New Stem Cell Gene Correction Process Puts Time on Researchers' Side Researchers Develop 'Killer Cells' to Destroy Cancer in Lymph Nodes New Study Provides Possible Way to Overcome Stem Cell Research’s Developmental Arrest Problem Novel Stem Cell Line Avoids Risk of Introducing Transplanted Tumors Researchers Find Greater Genetic Diversity Among Cancer Cells Than Anticipated Tissue Engineers Recruit Cells to Make Their Own Strong Matrix New Study: Leading Cause of Blindness Could Be Prevented or Delayed Rice U. Paper: End 'Stem Cell Tourism' Irx Genes Make Cartilage Cells Act 'Oh So Immature' Compound Protects Against Cell Damage That Leads to Macular Degeneration JEDI T-Cells Provide Unique Technology to Study, Visualize Immune Responses and Immunotherapies Study Sheds Light on Side Effects of COX-2 Drugs Hybrid Material that Responds to Heat and Light Presents Future Potential for 4D-Printed Adaptive Devices Guided Ultrasound Plus Nanoparticle Chemotherapy Cures Tumors in Mice Genetic Link Between Heart and Neurodevelopmental Disease New Tools Yield Superior Genome Analysis Results Safe Form of Estrogen Helped Multiple Sclerosis Patients Avoid Relapses TGen and Barrow Identify Genes Linked to Stress-Triggered Heart Disease Researchers Grow Retinal Nerve Cells in the Lab A Better Way to Grow Bone Cells How Cells in the Developing Ear 'Practice' Hearing Researchers Discover How Immune Cells Resist Radiation Treatment Umbilical Cells Help Eye’s Neurons Connect Immunotherapy for Type 1 Diabetes Deemed Safe in First US Trial High-Fat Diet Prompts Immune Cells to Start Eating Connections Between Neurons A Possible End to Eye Drops 5 Years and Growing: Regenerative Rehabilition Working in Collaboration to Prevent Blindness Retinal Regeneration Is a Fishy Problem New Test May Improve Diagnosis, Treatment of Pancreactic Cancers Stem Cell Treatment Mediates Immune Response to Spinal Cord Injury in Pre-Clinical Trials Biologists Characterize New Form of mRNA Regulation Can Stem Cell Technology Be Harnessed to Generate Biological Pacemakers? Eye Drops Could Clear Up Cataracts Using Newly Identified Chemical Cancer Cells Hijack Glucose, Alter Immune Cells Eye Drops Deliver Gene Therapy for Brain Disorders – NIH Mouse Study Embryonic Stem Cells and Artificial Stem Cells Are Functionally Equivalent Nanotechnology Could Spur New Heart Treatment for Arrthymia Bipolar Patients’ Brain Cells Predict Response to Lithium Targeting Invasive Cells Could Be a New Strategy to Treat Metastatic Cancer, Say Stony Brook Researchers Precursor Cells Discovered That Could Help Regrow Heart Arteries New Eye Structures Discovered Grant Award: Engineered Neovascularization of Vasa Vasorum Tumor RNA in Platelets May Diagnose and Classify Cancer, Identify Treatment Strategies New Computational Strategy Finds Brain Tumor-Shrinking Molecules A Prkci Gene Keeps Stem Cells in Check Discovery of Genes Involved in Inner Ear Development Hints at a Way to Restore Hearing and Balance Cardiac Muscle Cells as Good as Progenitors for Heart Repair Biologists Unravel Drug-Resistance Mechanism in Tumor Cells Gene Therapy Treats All Muscles in the Body in Muscular Dystrophy Dogs Stem Cell Biology and Gene-Editing Techniques Offer Hope for Kidney Regeneration Study Finds Thyroid Function May Be Restored Through Patient-Derived Human Cells A Subpopulation of White Blood Cells Guards Against Tumor Lung Metastasis Penn Dental Medicine Study Shows How Stem Cell Therapy Protects Bone in Lupus Gene Therapy Could Aid Weight Loss Without Affecting Bone Loss, New Research Finds Langmuir Features Work of Dr. Anna Balazs Chronic Arsenic Exposure Can Impair Ability of Muscle to Heal After Injury Something on Your Mind? Study Identifies Patients Most Likely to Have Joint Pain Reduction After Bariatric Surgery New Study Reveals How Specialized Cells Help Each Other Survive During Times of Stress Mechanism Identified for Enhancing Immunological Memory in Helper T Cells Scientists Find Way to Make Leukemia Cells Kill Each Other Scientists Make Advancements that May Lead to New Treatments for Parkinson's Looking at Retinal Cells May Provide New Approach to Assessing Anesthetic Neurotoxicity in Children Investigators Create Complex Kidney Structures from Human Stem Cells Derived from Adults Promising USC Study Focuses on Treatment for Dry Eyes Prostate Cells Undergo 'Reprogramming' to Form Tumors, Study Finds Researchers Gauge Heritability of Childhood-Onset Autoimmune Diseases Study Stops Vision Loss in Late-Stage Canine X-Linked Retinitis Pigmentosa Artificial Lung Demonstrates How Aerosols Move and Behave in Deepest Part of Lungs Huntington's Disease Protein Controls Movement of Precious Cargo Inside Cells, Study Finds Screen of Human Genome Reveals Set of Genes Essential for Cellular Viability Scientists Produce Clearest-Ever Images of Enzyme That Plays Key Roles in Aging, Cancer Stem Cell Treatment May Reduce Impairment Caused by Dementia Engineers Create Artificial Skin That Can Send Pressure Sensation to Brain Cell Special Class of T Cells Shown to Both Attack Cancer Cells and Enlist Other Immune Cells Sleep Deprivation Affects Stem Cells, Reducing Transplant Efficiency, Study Finds Blood T Cells Are Resistant to HIV's Primary Death Pathway Study Shows Deadly Prostate Cancer Cells Have Stem Cell Qualities Research: Epigenetic Factor Reduces Sensitivity of Breast Cancer Cells to Common Cancer Drug Scientists Engineer Stem Cells to Better Understand Mechanisms Behind Leukemia Throwback 1985: First Artificial Heart Used in Pittsburgh Bioprinting Soft Human Tissues Clinical Project Being Conducted at Walter Reed Pitt Spinout Company Wins 2015 Innovator of the Year—Life Sciences Tech 50 Award Pitt Hosts Representatives of the DoD Regenerative Medicine Traveling Exchange Program Pittsburgh’s 25th Anniversary of First VAD Patient to Be Discharged from a Hospital High Dose Chemo and Stem Cell Transplantation Result in Long-Term Survival for Amyloid Patients Researchers Learn How to Grow Old Brain Cells Johns Hopkins Biologist Leads Research Shedding Light on Stem Cells Virus-Drug Combination Shows Improved Effectiveness Against Brain Tumor Cells Approach or Buzz Off: Brain Cells in Fruit Fly Hold Secret to Individual Odor Preferences Scientists Test New Gene Therapy for Vision Loss from a Mitochondrial Disease Artificial Heart Design Features Porous Plastic Foam Dormant Viral Genes May Awaken to Cause ALS Scientists Identify Genes That Shut Down HIV-1 New Gene Therapy Approach to Treating DMD Reduces Symptoms, Extends Life Span in Mouse Model A Natural Light Switch ‘Remote Control’ of Immune Cells Opens Door to Safer, More Precise Cancer Therapies Sticky Gel Helps Stem Cells Heal Rat Hearts New Cancer Genes Identified, Opening Door to Targeted Treatments Metastatic Breast Cancer Cells Turn on Stem Cell Genes Arteries May Be Best Source for Detecting Circulating Tumor Cells Researchers Find Potential Source of Insulin-Producing Cells in Adult Human Pancreas Researchers Isolate Human Muscle Stem Cells Stem Cell-Derived ‘Organoids’ Help Predict Neural Toxicity Researchers Identify New Pathway to Regenerate Insulin-Producing Cells New Technique Lets Scientists See and Study the Interface Where Two Cells Touch Lab-Grown 3-D Intestine Regenerates Gut Lining in Pre-Clinical Trial Strengthening a Tiny Heart, Pound for Pound Pitt Researchers Are Working to Mass-Produce Stem Cells Grant: Regenerative Medicine Therapy for Abdominal Aortic Aneurysm Cancer Doesn't Sleep: MYC Oncogene Disrupts Clock, Metabolism in Cancer Cells E. Coli More Virulent When Accompanied by Beneficial Bacteria Network Control: Letting Noise Lead the Way Vaccine Clears Some Precancerous Cervical Lesions in Clinical Trial Diet, Exercise, Smoking Habits, and Genes Interact to Affect AMD Risk Exosomes Provide a Promising Way to Induce Human Stem Cell Differentiation In First, Scientists Use Sound Waves to Control Brain Cells Study Demonstrates Genes' Major Role in Skin and Organ Development Filling a Void in Stem Cell Therapy Switched Before Birth: Study Shows Protein Creates Tumor-Fighting Rather Than Tumor-Protecting Cells Bar-Coding Technique Opens Up Studies Within Single Cells Researchers Report Long-Term Remissions in First Personalized Cell Therapy Trial Silk Bio-Ink Could Help Advance Tissue Engineering with 3-D Printers Time-Lapse Analysis Offers New Look at How Cells Repair DNA Damage DNA-Guided 3-D Printing of Human Tissue is Unveiled Circuit in the Eye Relies on Built-in Delay to See Small Moving Objects Inducing Metabolic Catastrophe in Cancer Cells 'Eat Me' Signal Whets Appetites for Tumor-Devouring Dendritic Cells The Alien Within: Fetal Cells Influence Maternal Health During Pregnancy (and Long After) Degenerating Neurons Respond to Gene Therapy Treatment for Alzheimer's Disease Research with UWF Imaging May Change How Diabetic Eye Disease Is Assessed and Treated Synthetic Tissue Environment Enables Spatial Definition of Cancer Cells and Macrophages Imaging Techniques Set a New Standard for Super-Resolution in Live Cells Grant to Research Olfaction, Anosmia Awarded Novel Genes Found in Inflammatory Bowel Disease Under Age 5 Variations in Cell Programs Control Cancer and Normal Stem Cells Gene Therapy Fully Restores Vision in Mouse Model of Leber Congenital Amaurosis Newly Discovered Cells Regenerate Liver Tissue Without Forming Tumors Can Stem Cells Cause and Cure Cancer? New Clues Found to Vision Loss in Macular Degeneration? New Research Tool Tracks Real-Time DNA-Protein Binding in Cells Key Protein Drives 'Power Plants' That Fuel Cells in Heart and Other Key Body Systems Juvenile Arthritis: Why Genetic Risk Is Not in the Genes Digestible Batteries Needed to Power Electronic Pills Grant Received for the Alliance for Regenerative Rehabilitation Research & Training International Consortium for Regenerative Rehabilitation Leadership Council Established Studies into Mitigating Effects of Radiation to Continue Researchers Thwart Cancer Cells by Triggering 'Virus Alert' HIV Particles Do Not Cause AIDS, Our Own Immune Cells Do Vitamin D May Play Key Role in Preventing Macular Degeneration Algorithm Helps Identify Elusive Genes That Express Like Clockwork Researchers Find New Code That Makes Reprogramming of Cancer Cells Possible Screening for Breast/Ovarian Cancer Risk Genes Other Than BRCA1/2 is Clinically Valuable Asthma Cells Scramble Like 'There's a Fire Drill' Receptor That Helps Protect Brain Cells Has Important Role in Support Cells for the Retina New Computational Method Predicts Genes Likely to be Causal in Disease Study Provides Hope for Some Human Stem Cell Therapies NYBC, UC Davis Health System Partner to Manufacture Potential Stem Cell Therapies Contrary to Previous Studies, Diabetes Affects Diaphragm, Skeletal Muscle Cells Differently Joining Molecular Components Expands Ability to Manipulate Genes in Specific Cell Types In Uveitis, Bacteria in Gut May Instruct Immune Cells to Attack the Eye 'Jumping Genes' Unusually Active in Many Gastrointestinal Cancers, Studies Find Stanford Researchers Genetically Engineer Yeast to Produce Opioids Blood Vessel 'Doorway' Lets Breast Cancer Cells Spread Through Blood Stream Pancreas Cancer Spread From Multiple Types of Wayward Cells Drug Candidate Kills Cancer Cells through Overstimulation Gene Therapy Hope for Recurrent Ovarian Cancer Patients Dr. Anna Balazs’ Manuscript Chosen as an ACS Editors' Choice from All ACS Journals Children’s Hospital of Pittsburgh Foundation Invests in Cardiovascular Regeneration Research Protein-Hydrogel Combo May Help Heal Heart In Lab Tests, New Therapy Slows Spread of Deadly Brain Tumor Cells MSU Scientists Set Sights on Glaucoma Medication to Treat TB Patients' Own Genetically Altered Immune Cells Show Promise in Fighting Blood Cancer Stem Cells Have More Reserves for DNA Replication Tiny Brain Clumps Offer New Clues into the Cause of Autism Vision-Restoring Gene Therapy Also Strengthens Visual Processing Pathways in Brain, According to Penn Study OHSU Scientists Unlock First Step Towards Gene Therapy Treatment of Mitochondrial Disease Research Finds Ovarian Hormones Play Genes Like a Fiddle Adults Harbor Lots of Risky Autoreactive Immune Cells, Study Finds New Techniques for Reprogramming Stem Cells Target Neurological Disease Models Printing 3-D Graphene Structures for Tissue Engineering What Makes Cancer Cells Spread? New Device Offers Clues Lung Cell Phenotype Reverts When Seeded Onto Decellularized Lung Matrix Registration Now Open: 2015 Symposium--Regenerative Surgery: The Cutting Edge Studying the Advances in Next-Generation Stem Cell Culture Technologies Pitt Researchers Will Study Sepsis with $1.5M NIH Grant Pitt’s Center for Medical Innovation Awards Round-1 2015 Pilot Funding New High Definition Fiber Tracking Preserving Photoreceptor Cells Following Retinal Injury Using Low-Dose Irradiation, Researchers Can Now Edit Human Genes Imaging Glucose Uptake Activity Inside Single Cells Dental Researchers Find Some Immune Cells Change to Prolong Inflammation Pilot Clinical Trial Finds Injected Immune Cells Safe in Multiple Myeloma Patients Microchip Captures Clusters of Circulating Tumor Cells Bigger Capsules May Be Long-Sought Key for Transplanting Islet Cells Programming Adult Stem Cells to Treat Muscular Dystrophy and More by Mimicking Nature Stem Cells Move One Step Closer to Cure for Genetic Diseases Researchers Poke Around for Blood Genes Nanoparticle Transport System for Genes Thwarts Brain Cancer in Rats Study Finds Vitamin A Directs Immune Cells to the Intestines Biomaterial Scaffold Implanted After Spinal Cord Injury Promotes Nerve Regeneration Disrupting Cells’ ‘Powerhouses’ Can Lead to Tumor Growth, Penn Study Finds Age-Related Self-Destruction of Cells Makes Kidney Prone to Injury New Publications Show Promise of Improved Artificial Lung Devices Save the Date: 9th Symposium on Biologic Scaffolds for Regenerative Medicine Subset of Plasma Cells Represent 'Historical Record' of Childhood Infections Researchers Create Model of Early Human Heart Development from Stem Cells Stem Cells Provide Lasting Pain Relief in Mice Bonelike 3-D Silicon Synthesized for Potential Use with Medical Devices Researchers Identify Critical Genes Responsible for Brain Tumor Growth Sculpting a Cell's Backside: New Protein Found to Help Cells Move from Behind Enriched Blood Cells Preserve Cognition in Mice with Features of Alzheimer's Disease Researchers Explore How Sox9 Protein Regulates Production of Cartilage City of Hope Researchers to Use Patients' Own Modified T Cells to Treat Advanced Brain Tumors LSD1 Enzyme Turns Off Genes Needed to Maintain Cancer Stem Cell Properties in Glioblastoma Study Shows That Microglia Can Accelerate Damage Wrought by Blinding Eye Disorders Study of Gene Mutations in Aplastic Anemia May Help Optimize Treatment Discovery of Nanotubes Offers New Clues About Cell-to-Cell Communication Research Finds Protein Regulation Linked to Cells' Growth Cycle Seeking Rare Cells Study Shows Acute Pulmonary Fibrosis May Respond to Autoimmune Disease Therapy Beyond Average: New Platforms Genetically Barcode Tens of Thousands of Cells at a Time Elastic Gel to Heal Wounds Genes May Not Be to Blame for Link Between Migraine and Heart Disease New Measurements Reveal Differences Between Stem Cells for Treating Retinal Degeneration Scientists Develop Potential New Class of Cancer Drugs in Lab Research Team Finds Different Immune Response in Severe Asthma Team Programs Solitary Yeast Cells to Say ‘Hello’ to One Another Stem Cell Gene Therapy Developed at UCLA Holds Promise for Eliminating HIV Infection Stanford Team Develops Technique to Magnetically Levitate Single Cells Researchers Uncover Epigenetic Switches that Turn Stem Cells into Blood Vessel Cells MARCKS Protein May Help Protect Brain Cells from Age Damage Skip a Beat? Your Auditory Nerve Cells Will Know It Dr. Anna Balazs: NSF Interview Exploring the Future of Eye Transplantation Type 2 Diabetes Remission for Bariatric Surgery Researchers ID Best Source of Stem Cells to Block Diabetic Blindness Targeting Telomeres, the Timekeepers of Cells, Could Improve Chemotherapy Cells Too Stiff to Scavenge Leads to Lupus, an Autoimmune Disease Human Cells Used to Create Disease Model of Fully Functioning Lipid System in Mouse Model Returning Killer T Cells Back to Barracks Could Improve Vaccines New Stem Cell Population Important in the Growth of Colon Cancer Identified Bascom Palmer Researchers Discover Protein that Leads to Glaucoma Pneumonia Found to Harm DNA in Lung Cells Tuberculosis Bacteria Hide in the Low Oxygen Niches of Bone Marrow Stem Cells Computer Simulation Predicts Development, Progress of Pressure Sores What Your Clothes May Say About You Safety Switch Preserves Beneficial Effects of Cell Therapy Drug Perks Up Old Muscles and Aging Brains Study Shows Role of Disease-Fighting Cells in HIV-Related Neurological Damage Gene Found That Is Essential to Maintaining Breast and Cancer Stem Cells Master Orchestrator of the Genome is Discovered, UB Stem Cell Scientists Report Mutations in Two Genes Linked to Familial Pulmonary Fibrosis and Telomere Shortening Odd Histone Helps Suppress Jumping Genes in Stem Cells, Study Says Gene Therapy Benefits for Some Vision Disorder Patients Peak, Then Decline Tuning Cells in the Key of G Proteins U.S. Clinics Avoiding Government Oversight of 'Stem Cell' Treatments Protein in Metabolic Reprogramming Restrains Senescent Cells from Becoming Cancerous Vital Step in Stem Cell Growth Revealed: Finding Could Aid Regenerative and Cancer Therapies Scientists Find Way to Monitor Progress of Stem Cells After Transplantation Into Brain Researchers Use 'Knockout Humans' to Connect Genes to Disease Risk Researchers Deliver Large Particles Into Cells at High Speed More Anti-inflammatory Genes Mean Longer Lifespans for Mammals Neural Stem Cell Implants Hold Promise for Treating Epilepsy Key Tissue Engineering Step Taken in Forming New Blood Vessels Scientists Observe Deadly Dance Between Nerves and Cancer Cells Nerve Cells, Blood Vessels in Eye 'Talk' to Prevent Disease Study Reveals How FOXO1 Slows Diabetic Wound Healing More Power to the Mitochondria: Cells' Energy Plant Also Plays Key Role in Stem Cell Development Understanding How Nerve Cells in the Brain Produce Energy Required to Function Stem Cell-Based Therapy Promising for Treatment of Breast Cancer Metastases in the Brain Investigators Show How Immune Cells Are 'Educated' Not to Attack Beneficial Bacteria Dead Feeder Cells Support Stem Cell Growth Nanotech-Enabled Moisturizer Speeds Healing of Diabetic Skin Wounds Tumor Cells that Mimic Blood Vessels Could Help Breast Cancer Spread to Other Sites Defect Found in Pancreatic Cells Could Lead to New Diabetes Treatment Contact Lens Sensor Safe for Patients with Thyroid Eye Disease Gene Therapy Clips Out Heart Failure Causing Gene Mutations New Therapy from Naive Cells Attacks High-Risk Viruses in Cord Blood Transplant Patients How an RNA Gene Silences a Whole Chromosome Prenatal Stem Cell Treatment Improves Mobility Issues Caused by Spina Bifida Ultrasound Settings Can Change Beat Frequency of Cardiac Cells Pancreatic Cancer Breakthrough: Scientists Turn Cancer Cells Into Normal Cells Drugs That Activate Brain Stem Cells May Reverse Multiple Sclerosis Angiogenesis Inhibitors Undermined by Immune Cells, Says Study Virtual Reality May Be Effective Tool for Evaluating Balance Control in Glaucoma Patients New Transitional Stem Cells Discovered Stem Cell Treatment Repairs Birth Defect, Provides Facial Regeneration for People Suffering Traumatic Injury Immune Cells Help 'Good Bacteria' Triumph Over 'Bad Bacteria' in the Gut How Breast Cancer Cells Avoid Cell Death Research Finds No Correlation Between Regulatory T Cells and Survival in Glioblastoma Scientists Uncover How Molecule Protects Brain Cells in Parkinson's Disease Model Stem Cell Scientists Develop More Effective Way to Create Motor Neurons Stem Cell Injection May Soon Reverse Vision Loss Due to Age-Related Macular Degeneration Gold by Special Delivery Intensifies Cancer-Killing Radiation Genetically Modified Salmonella Can Help Kill Cancer Cells Cancer Virology Researchers Reveal New Pathway That Controls How Cells Make Proteins One Type of Airway Cell Can Regenerate Another Lung Cell Type A New Tool for Understanding ALS: Patients' Brain Cells Encapsulated Stem Cells Accelerate Wound Healing Scientists Visualize Potential Brain Cancer Treatments in Real Time with Nanotechnology New Study Could Hold Key to Control Growth of Cancer Cells Stem Cell Disease Model Clarifies Bone Cancer Trigger Gut Instinct: How Intestinal Stem Cells Find Their Niche Amniotic Stem Cells Demonstrate Healing Potential A Digital Field Guide to Cancer Cells Team Discovers Novel Mechanism Controlling Lung Cancer Stem Cell Growth Common Cancers Highjack Powerhouses of Cells Age-Discrimination During Cell Division Maintains the 'Stem' in Stem Cells New Way to Sort Cells Without Limitations of Traditional Methods Cells Exercise Suboptimal Strategy to Survive New Advancements in 3D Designs for Neural Tissue Engineering Device Extracts Rare Tumor Cells Using Sound Mitochondria Are Altered in Human Cell Model of Parkinson's Disease Protein Determines Life or Death Fate of Stressed Cells Researchers Identify "Beige" Fat-Burning Cells in Humans Microsecond Raman Imaging Might Probe Cells, Organs for Disease Premature Aging of Stem Cell Telomeres, Not Inflammation, Linked to Emphysema MRI Based on a Sugar Molecule Can Tell Cancerous From Noncancerous Cells Specific Roles of Adult Neural Stem Cells May Be Determined Before Birth A Single Gene Turns Colorectal Cancer Cells Back Into Normal Tissue in Mice Scientists Identify Progenitor Cells for Blood and Immune System Using Stem Cell Exosomes to Induce Damaged Mouse Hearts to Repair Themselves Without Stem Cell Risk Protein Plays Unexpected Role in Embryonic Stem Cells Disabling Infection-Fighting Immune Response Speeds Up Wound Healing in Diabetes Gene Therapy Prevents Parkinson’s Disease in Animal Model, Says Pitt Study Researchers Develop New Technique for Modeling Neuronal Connectivity Using Stem Cells Penn Researchers Show How Cells Solve Biochemical Challenges as They Get Bigger Help Pitt Researchers Keep Organs Alive for Transplantation Osteosarcoma: What Is It and How Is It Treated? Hyperbaric Oxygen Therapy for Wound Healing Dendritic Cells of Elite Controllers Able to Recognize, Mount Defense Against HIV Researchers Devise a Better Way to Potentially Avert Blindness Certain Donors with High T Cell Counts Make a Better Match for Stem-Cell Transplant Patients, Penn Study Suggests Researchers Identify Patients at Risk for Stem Cell Transplant Complications ‘Genomic Catastrophe' May Cause Normal Cells to Become Cancerous Rabbit Virus Improves Bone Marrow Transplants, Kills Some Cancer Cells Autologous Stem Cell Therapy Helpful in Traumatic Brain Injury New Model, New Choices for Wound Healing Using Electrical Fields Human Stem Cell Model Reveals Molecular Cues Critical to Neurovascular Unit Formation How Dividing Cells End Up the Same Size You're As Old As Your Stem Cells Penn Researchers Home In on What's Wearing Out T Cells Tough Biogel Structures Produced By 3-D Printing Study Identifies Possible Role for Carbon Monoxide in Treating Hemorrhagic Stroke Non-Aqueous Solvent Supports DNA Nanotechnology Zebrafish Model Gives New Insight on Autism Spectrum Disorder Tiny Spheres of Human Cells Mimic the Brain, Researchers Say Researchers Identify Origin of Chromosomal Oddity in Some Cancer Cells Regenerating Diminished Skeletal Muscle Tissue Lower Birth Weight Associated with Proximity of Mother’s Home to Gas Wells Designing 3D-Printed Materials to Help the Body Heal Itself Stem Cell and Epigenetic Strategies for Retinal Repair Computer Simulation Accurately Replicated Real-Life Trauma Outcomes Statistical Approach Able To Pinpoint Real from Artifact Alerts Designing a Synthetic Gel that Changes Shape and Moves via Its Own Internal Energy Massive Weight Loss Surgery Highlighted Study Adds Evidence on Link Between PTSD, Heart Disease Mount Sinai Researchers Discover Genetic Origins of Myelodysplastic Syndrome Using Stem Cells How the Human Immune System Keeps TB at Bay Novel Nanoparticle Therapy Promotes Wound Healing Common Bacteria on Verge of Becoming Antibiotic-Resistant Superbugs Brain Tumor Cells Decimated by Mitochondrial "Smart Bomb" TSRI Team Discovers Enzyme That Keeps Blood Stem Cells Functional to Prevent Anemia For Most Children with HIV and Low Immune Cell Count, Cells Rebound After Treatment University of Michigan Scientists Grow First 3D Mini Lungs from Human Stem Cells Gene Therapy Slows Vision Loss in Mouse Models of Retinal Degeneration New Score Predicts Heart Disease and Stroke Risk for Anyone in World Aged Over 40 Study Reveals Functional Heterogeneity of CD4 T Cells in Immune Systems Team Finds Key to Making Neurons from Stem Cells Scientists Pinpoint Molecule That Controls Stem Cell Plasticity by Boosting Gene Expression Vitamin D Helps Immune Cells Prevent Atherosclerosis and Diabetes Researchers Identify Protein Needed for Repair of Injured Kidney Cells UT Southwestern Neuroscientists Identify Key Brain Cells That Control Circadian Rhythms Researchers Change Human Leukemia Cells Into Harmless Immune Cells Researchers Find 'Affinity Switch' for Proteasome Assembly Process in Cells When Cancer Cells Stop Acting Like Cancer Donor Supports Research Addressing Dupuytren’s Disease Modeling How Cells Move Together Could Inspire Self-Healing Materials New Technique Can Locate Genes' On-Off Switches Researchers Develop 'Warhead' Molecule That Targets Deadly Bacteria, Spares Healthy Cells Study: New Gene Therapy Safe, Effective for Patients with Hemophilia B Stem Cells Lurking in Tumors Can Resist Treatment Boosting a Natural Protection Against Alzheimer's Disease Immune System-in-a-Dish Offers Hope for 'Bubble Boy' Disease Scientists Show Proteins Critical in Day-Night Cycles Also Protect Cells from Mutations New Class of Drugs Dramatically Increases Healthy Lifespan, Mouse Study Suggests High-End Imaging: New Blending Techniques Magnetic Nanoparticles Could Allow Brain Stimulation Without Wires Why Do Cells Rush to Heal a Wound? Mysteries of Wound Healing Unlocked Rett Syndrome May Result from Overexpression of Long Genes Novel Drug Candidate Regenerates Pancreatic Cells Lost in Diabetes First Look at Hospitalized Ebola Survivors' Immune Cells Could Guide Vaccine Design New Protein Booster May Lead to Better DNA Vaccines and Gene Therapy Under Our Nose: Supplemental Oxygen Can Make Tumors Shrink, Says New Study Researchers Identify Genes Responsible for Lung Tumors New Nanodevice Defeats Drug Resistance: Tiny Particles Embedded in Gel Can Turn Off Drug-Resistance Genes, Then Release Cancer Drugs Restoring Ability to Halt Cell Division May Protect Lung Cells from Cancer Researchers Identify Protein Pathway Involved in Brain Tumor Stem Cell Growth Yale Researchers Reverse Type 2 Diabetes and Fatty Liver Disease in Rats Small Molecule Helps Get Stem Cells to Sites of Disease and Damage Do Genes Play a Role in Peanut Allergies? New Study Suggests Yes Neurons Controlling Appetite Made From Skin Cells Asian Herb Holds Promise as Treatment for Ebola Virus Disease Growth Signal Can Influence Cancer Cells' Vulnerability to Drugs, Study Suggests HIV Controls Its Activity Independent of Host Cells Widely Used Food Additives Promotes Colitis, Obesity, and Metabolic Syndrome, Shows Study of Emulsifiers New TSRI Study Shows Safer Methods for Stem Cell Culturing Immune Cells: Learning From Experience Researchers Identify Gene That Pushes Normal Pancreas Cells to Change Shape Dental Researcher Demonstrates How T Cells Cause Inflammation During Infections Vision Loss Reversed in People with Diabetic Eye Disease Researchers Find Drugs Are Effective for Diabetic Macular Edema in New Trial New Nanogel for Drug Delivery: Self-Healing Gel Can Be Injected Into the Body and Act as a Long-Term Drug Depot Proteins Pull Together as Cells Divide Development of Personalized Cellular Therapy for Brain Cancer Epigenome of More Than 100 Tissue and Cell Types Mapped Human Neural Stem Cells Restore Cognitive Functions Impaired by Chemotherapy Study Reports New Gene Therapy Approach Ingredient in Olive Oil Kills Cancer Cells with Their Own Enzymes Bioresorbable Metals in Regenerative Medicine Pitt Collaborates with Janssen to Study and Tailor New Treatments for Inflammatory Bowel Disease From Bench to Bedside: Technology Developed by McGowan Faculty Used in Clinical Setting Physical Therapy, Surgery Produce Same Results for Stenosis in Older Patients A Strategy for Stimulating Heart Muscle Regeneration in Infants, Study Finds Vanderbilt and Pittsburgh to Lead New Center to Identify Toxic Chemicals Catching and Releasing Tiny Molecules McGowan Institute for Regenerative Medicine: 2015 Annual Scientific Retreat Rebooting Cell Programming Can Reverse Liver Failure Early Retina Cell Changes in Glaucoma Identified One-Two Punch Catches Cancer Cells in Vulnerable State Engineers Put the 'Squeeze' on Human Stem Cells How Tumor-Causing Cells Are Recruited in Cancers Linked to Chronic Inflammation Researchers Uncover Signal That Switches Cells to Cancerous Metabolism Akt Pathway 'Ramp Ups' Effects of Transplanted Umbilical Cord Cells Used in Stroke Therapy Light-Activated Genes Might Be Precisely Controlled and Targeted New Study Sheds Light on Cancer Stem Cell Regulation New Source of Cells for Modeling Malaria Study Highlights Brain Cells' Role in Navigating Environment Study Ties Immune Cells to Delayed Onset of Post-Stroke Dementia A Few Cells Could Prevent Bone Marrow Transplant Infections New Nanoparticle Gene Therapy Strategy Effectively Treats Deadly Brain Cancer in Rats Serendipity Leads to Discovery of Adult Cancer Genes in Young-Adult Ewing Sarcoma New Study Shows How Immune Cells Hone Their Skills to Fight Disease Latent HIV May Lurk in 'Quiet' Immune Cells, Research Suggests Researchers Identify Molecular Mechanisms That Can Prevent Blindness, Promote Recovery from Stroke New Cancer-Fighting Strategy Would Harden Cells to Prevent Metastasis Common Degenerative Eye Disease May Be Triggered by Tiny Mineral Deposits Green Tea Ingredient May Target Protein to Kill Oral Cancer Cells New Cells May Help Treat Diabetes Using Stem Cells to Grow New Hair Penn Dental Medicine Team Shows Why Wound Healing Is Impaired in Diabetics Prostate Cancer: Androgen Receptor Activates Different Genes When Bound to Antiandrogens Rare Neurological Disease Shines Light on Health of Essential Nerve Cells Telomere Extension Turns Back Aging Clock in Cultured Human Cells, Study Finds Genome-Wide Search Reveals New Genes Involved in Long-Term Memory Genes Linked to Brain Size May Help Explain Some Neurological Diseases Rice Researchers Develop New Version of Hydrogel to Promote Wound Healing Stem Cell Transplantation Shows Potential for Reducing Disability in Patients with Multiple Sclerosis Gene Therapy-Associated Cancer Incidence Depends on Vector Design Environment, Not Genes, Dictates Human Immune Variation, Research Finds Scientists Use 'Nanovelcro' and Temperature Control to Extract Tumor Cells from Blood Scientists Discover Gene Tied to Profound Vision Loss New Insight That 'Mega' Cells Control the Growth of Blood-Producing Cells Immune Cells May Help Treat Muscular Dystrophy, UCSF-Led Team Finds Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied Pitt to Lead $14M National Trial Comparing Approaches to Treat Back Pain, Avoid Surgery CMU’s Biomedical Engineering Department to Create Heart Science Program Neuroprotecting and Repairing Injured Retina and Optic Nerve with ECM Stem Cells from Wisdom Teeth Can Be Transformed into Corneal Cells Metabolic Disorder Treatment Through Liver Cell Transplant Enterovirus D68 Seen in Cancer, Stem Cell Transplant Patients Researchers Identify That OCR Stem Cells Can Regenerate Bone and Cartilage in Mice Vaccine-Induced CD4 T Cells Have Adverse Effect in a Mouse Model of Infection Nanopore Device Allows for Manipulation of Differentiating Stem Cells Study IDs Two Genes That Boost Risk for Post-Traumatic Stress Disorder Mechanical Stress Produces ‘Stem-Like’ Cells Via Nontoxic Method HIV Vaccines Should Avoid Viral Target Cells, Primate Model Study Suggests Immune Cells Proposed as HIV Hideout Don't Last in Primate Model Heart Drug May Help Treat Amyotrophic Lateral Sclerosis, Mouse Study Shows Anti-Cancer Drug Effective Against Common Stem Cell Transplant Complication Molecular Beacons Shine Light on How Cells 'Crawl' Progression of Age-Related Macular Degeneration in One Eye Then Fellow Eye Scientists Discover Hidden Subpopulation of Melanoma Cells New Genome-Editing Technique Enables Rapid Analysis of Genes Mutated in Tumors Scientists Discover Hidden Subpopulation of Melanoma Cells Human Skin Cells Reprogrammed Directly Into Brain Cells Once CD8 T Cells Take on One Virus, They'll Fight Others Too Blind Cave Fish May Provide Insight on Eye Disease and Other Human Health Issues Crystallizing the DNA Nanotechnology Dream First Step: From Human Cells to Tissue-Engineered Esophagus Nanoparticle-Based Photodynamic Therapy to Effectively Kill Deep-Set Cancer Cells In Vivo Pitt Team Developing Technology to Allow Amputees to Feel with Prosthetic Limb, Improving Its Function TissuGlu: First Tissue Adhesive Approved by FDA for Internal Use Erectile Dysfunction Drugs Could Protect Liver from Sepsis-Induced Damage Hacking Fat Cells' Metabolism Does Not Affect Insulin Resistance UCLA Researchers Develop Method That Defines Unique Stages of Reprogramming Skin Cells 'Glowing' New Nanotechnology Guides Cancer Surgery, Also Kills Remaining Malignant Cells Retinal-Scan Analysis Can Predict Advance of Macular Degeneration, Stanford Study Finds New e-Incubator Enables Real-Time Imaging of Bioengineered Tissues in Controlled Unit NSAIDs Prevent Colon Cancer by Inducing Death of Intestinal Stem Cells That Have Mutation New Material Advances Tissue Engineering, Drug Delivery Researchers Use Nanotechnology to Engineer ACL Replacements Research Sheds Light on What Causes Cells to Divide Test Predicts Response to Treatment for Complication of Leukemia Stem Cell Treatment New Way to Turn Genes On Genetically Modified Cells Learn to Fight Mesothelioma Researchers Find Way to Defeat Elusive Target Proteins in Cancer Cells Reprogrammed Cells Grow Into New Blood Vessels Researchers Grow Norovirus in Human Cells Scientists Develop New Way to Study How Human Cells Become Immortal, a Crucial Precursor to Cancer Direct Generation of Neural Stem Cells Could Enable Transplantation Therapy Scientists Find That SCNT Derived Cells and IPS Cells Are Similar Retinal Neuron Survival in Glaucoma Production of Human Motor Neurons from Stem Cells Gaining Speed Researchers Discover New Class of Stem Cells How Cartilage Cells Sense Forceful Injury Scientists Uncover a Role for Carbon Monoxide in Battling Bacterial Infections Team Genetically 'Edits' Human Blood Stem Cells Can Patients With Graves Disease Minimize Their Risk for Developing Thyroid Eye Disease? Cells Identified That Enhance Tumor Growth and Suppress Anti-Cancer Immune Attack Study Shows How Breast Cancer Cells Break Free to Spread in the Body Proteins Drive Cancer Cells to Change States Baby Cells Learn to Communicate Using the Lsd1 Gene Decoding Fat Cells: Discovery May Explain Why We Gain Weight Senescent Cells Play an Essential Role in Wound Healing Yeast Are First Cells Known to Cure Themselves of Prions Blocking Receptor in Brain’s Immune Cells Counters Alzheimer’s in Mice, Study Finds Turning Biological Cells to Stone Improves Cancer and Stem Cell Research Penn Vet-Berkeley Study: New Therapy Holds Promise for Restoring Vision Gravity: It's the Law, Even for Cells Work on Key Protein Suggests Ways to Address Wound Healing and Autoimmune Disease Predicting the Storm: Can Computer Models Improve Stem Cell Transplantation? Scientists Uncover Mechanism That Controls the Fitness of Cells, Impacting Aging and Disease Tumor Suppressor Also Inhibits Key Property of Stem Cells Scientists Discover New Properties of Microbes That Cause Common Eye Infection Team Finds Novel Approach to Treating Age-Related Macular Degeneration New Machine-Perfusion Organ Preservation System Keeps Livers Healthier for Transplant Statins Inhibit Spread of Some Cancers in Laboratory Tests Smoking, Alcohol, Gene Variant Interact to Increase Risk of Chronic Pancreatitis Stem Cells Faulty in Duchenne Muscular Dystrophy, Researchers Find New Mechanism that Helps Explain Why Older Patients Develop Lung Fibrosis Discovered Company Spotlight: Procirca Wheelchair-Mounted Mobile Robotic-Assisted Transfer System Project: Create Global Network to Improve Lives of Wheelchair Users New Single-Cell Analysis Reveals Complex Variations in Stem Cells Researchers Pinpoint Chemo Effect on Brain Cells, Potential Link to Autism Cancer Uses Abdominal Stem Cells to Fuel Growth and Metastasis 'Chatty' Cells Help Build the Brain Finding Could Upend Scientific Consensus About When Embryonic Cells Begin Separating Into Cell Types The Role DNA Methylation Plays in Aging Cells Infection-Fighting B Cells Go With the Flow Anti-Cancer Drug Protects Normal Cells from Radiation Damage, Increases Effectiveness of Radiation Therapy A Highly Robust, Efficient Nanoparticle-Based Platform to Advance Stem Cell Therapeutics Snapshot of Funded Research: Highlights for 2014 Novel Biomedical Device Receives Funding Patient’s Own Stem Cells Could Clear a Cloudy Cornea 'Wound Response' of Cancer Stem Cells May Explain Chemo-Resistance in Bladder Cancer Researchers Recreate Stem Cells From Deceased Patients to Study Present-Day Illnesses Scientists Convert Human Skin Cells Into Sensory Neurons Scientists Identify Bone Cells That Could Help Children Who Need Corrective Facial Surgery Pluripotent Cells Created by Nuclear Transfer Can Prompt Immune Reaction, Researchers Find Panel-Based Genetic Diagnostic Testing for Inherited Eye Disease Proves Highly Accurate Cells' Natural Response to Chronic Protein Misfolding May Do More Harm Than Good Masking HIV Target Cells Prevents Viral Transmission in Animal Model Researchers Identify Protein Key to the Development of Blood Stem Cells Signaling Molecule Crucial to Stem Cell Reprogramming Study Finds Link Between Neural Stem Cell Overgrowth and Autism-Like Behavior in Mice Nanoparticles Get a Magnetic Handle: Glowing Nanoparticles Can Be Manipulated Using Magnetic Fields Study Finds Potential Link Between Breast Cancer Genes and Salivary Gland Cancer Scientists Discover Pain Receptor on T-Cells Memory Loss Associated With Alzheimer's Reversed: Small Trial Succeeds Using Systems Approach to Memory Disorders Scientists Manipulate Split Proteins to Detect Interactions in Living Cells 'Unsung' Cells Double the Benefits of a New Osteoporosis Drug Barcoding Tool for Stem Cells: New Technology That Tracks the Origin of Blood Cells Challenges Scientific Dogma Stochastic Variations of Migration Speed Between Cells in Clonal Populations New Gene Therapy for 'Bubble Boy' Disease Appears Effective, Safe Manipulating Memory with Light: Scientists Erase Specific Memories in Mice Study Reveals How Deadly MERS Virus Enters Human Cells A New Way to Extract Bone-Making Cells from Fat Tissue Researchers Develop Novel Gene / Cell Therapy Approach for Lung Disease Research Shows Viral DNA Infects Cells by Changing From Solid to Fluid-Like State Biomarker for Diabetic Eye Disease BRD4 Protein Appears to Play Key Role in Keeping Stem Cells in Immature "Pluripotent" State Scientists Use Stem Cells to Learn How Common Mutation in Asians Affects Heart Health First-Ever Liver Transplant to Treat AHCY Deficiency Performed Pitt Innovation Challenge Awards Prizes to Creative Thinkers Scientists Identify Key Factor That Maintains Stem Cell Identity Bacterial 'Communication System' Could Be Used to Stop and Kill Cancer Cells Chemists Recruit Anthrax to Deliver Cancer Drugs Cancer Cells Adapt Energy Needs to Spread Illness to Other Organs A Better Way to Track Emerging Cell Therapies Using MRIs Scientists Discover an On/Off Switch for Aging Cells Hey1 and Hey2 Ensure Inner Ear 'Hair Cells' Are Made at the Right Time, in the Right Place Final Pieces to the Circadian Clock Puzzle Found Cells Put Off Protein Production During Times of Stress Combining Antibodies, Iron Nanoparticles, and Magnets Steers Stem Cells to Injured Organs Milestone Reached in Work to Build Replacement Kidneys in the Lab In Directing Stem Cells, Study Shows Context Matters Scientists Identify How Immune Cells Use Two Critical Receptors to Clear Dead Cells from the Body Researchers Measure Stiffness of Membrane Surrounding Red Blood Cells Over Time How to Tell Good Stem Cells from the Bad Scientists Identify Rare Stem Cells That Hold Potential for Infertility Treatments Scientists Map Protein in Living Bacterial Cells Study Discovers New Therapeutic Target for Diabetic Wound Healing 'Prepped' by Tumor Cells, Lymphatic Cells Encourage Breast Cancer Cells to Spread Researchers Find Way to Take Pediatric Patient's Skin Cells Scientists Make Diseased Cells Synthesize Their Own Drug Scientists Call For Investigation of Mysterious Cloud-Like Collections in Cells Gene Clues to Glaucoma Risk Malaria’s Clinical Symptoms Fade on Repeat Infections Due to Loss of Immune Cells, UCSF-Led Team Finds Attacking a Rare Disease at its Source With Gene Therapy Eye Implant Developed at Stanford Could Lead to Better Glaucoma Treatments Sorting Cells with Sound Waves Scientists Uncover Navigation System Used by Cancer, Nerve Cells First Clinical Trial for New Skin Wound-Healing Compound Is a Success Using Molecular Imaging Probes Diabetic Retinopathy Can Be Detected at Molecular Level Research Shows How Premalignant Cells Can Sense Oncogenesis and Halt Growth Study Shows Native American Ancestry a Risk Factor for Eye Disease Stem Cell Therapies Hold Promise, But Obstacles Remain Gene Therapy Protects Mice from Heart Condition Biologists Reprogram Skin Cells to Mimic Rare Disease Moving Single Cells Around—Accurately and Cheaply Sequencing Immunoglobulin Genes to Detect Residual Traces of Cancer Suspect Gene Corrupts Neural Connections Researchers Review Potential of Adipose-Derived Stem Cells to Improve Nerve Regeneration Genetic Signal Prevents Immune Cells from Turning Against the Body How Breast Cancer Usurps the Powers of Mammary Stem Cells Microchip Reveals How Tumor Cells Transition to Invasion Hippo Pathway Identifies and Prevents Progression of Abnormal Cells into Cancer Scientists Create Computer Algorithm for Cell and Tissue Engineering Bioengineers: Matrix Stiffness Is an Essential Tool in Stem Cell Differentiation Research Findings May Lead to Novel Target for Chemoresistant Cancer Cells An Easier Way to Manipulate Malaria Genes Team Reveals Molecular Competition Drives Adult Stem Cells to Specialize Single-Cell Analysis Holds Promise for Stem Cell and Cancer Research Growing Human GI Cells May Lead to Personalized Treatments Advanced Thin-Film Technique Could Deliver Long-Lasting Medication Master HSF Supports Reprogramming of Normal Cells to Enable Tumor Growth and Metastasis Researchers Discover Universal Molecular 'Flag' That Highlights Critical Genes Beware of Claims About Cosmetic Stem Cells Procedures, Review Says Gene Therapy Boosts Chemotherapy Tolerance and Effectiveness of Medications That Attack Brain Cancer Editing HPV's Genes to Kill Cervical Cancer Cells Cancer Cells Look for a Soft Bed How Ageing Blood Stem Cells Lose Function Sugar Mimics Guide Stem Cells Toward Neural Fate Study Identifies Genes Linked to Breast Cancer in East Asian Women Distinctive Developmental Origin for a Drainage Tube in the Eye Aggressive Tumors Silence Genes That Fight Cancer Investigators Identify Genes That Contribute to Radiation Resistance Scientists Eliminate the HIV Virus from Cultured Human Cells for First Time Iodine May Alleviate Swelling in Retinitis Pigmentosa Patients' Retinas Target Growth-Driving Cells Within Tumors, Not Fastest-Proliferating Cells Gene Changes in Breast Cancer Cells Pinpointed with New Computational Method Stem Cells Aid Muscle Repair and Strengthening After Resistance Exercise Researchers Create New Method to Draw Molecules from Live Cells Neurons, Brain Cancer Cells Require the Same Little-Known Protein for Long-Term Survival Cells’ Protective DNA Linked to Size of Brain Region Vital For Memory Scientists Find Genetic Recipe to Turn Stem Cells to Blood Diagnosing Type 1 Diabetes with Nanotechnology Stem Cell Scientists Lay a TRAP for Disease Acute Glaucoma Discovered to Be an Inflammatory Disease Stem Cell Researcher Targets the 'Seeds' of Breast Cancer Metastasis New Gene Therapy May Be Effective for Fighting Fungal Infections in Cancer Patients Researchers Regrow Human Corneas: First Known Tissue Grown From a Human Stem Cell Discovery May Make it Easier to Develop Life-Saving Stem Cells Transplantation of New Brain Cells Reverses Memory Loss in Alzheimer's Disease Model Patient-Specific Stem Cells and Personalized Gene Therapy Human Cells' Protein Factory Has an Alternate Operating Manual Some Stem Cell Methods Closer to 'Gold Standard' Than Others Research Team Pursues Techniques to Improve Elusive Stem Cell Therapy The Social Psychology of Nerve Cells: Researchers Explore the Genetic Underpinnings of Nerve-Cell Spacing Scientists Find Potential New Use for Cancer Drug in Gene Therapy for Blood Disorders Glaucoma Drug Helps Restore Vision Loss Linked to Obesity Stem Cells May Be More Widespread and With Greater Potential Than Previously Believed Taking Immune Cells for a Test Drive An Equation to Describe the Competition Between Genes Cancer Cells Don't Take 'Drunken' Walks Through the Body Scientists 'Herd' Cells in New Approach to Tissue Engineering Biomolecular Tweezers Facilitate Study of Mechanical Force Effects on Cells and Proteins Several FDA-Approved Anti-Cancer Drugs Induce Stem Cell Tumors, Perhaps Thwarting Therapy Researchers Identify Candidate Genes Associated With Free Radicals Alzheimer’s Research Team Employs Stem Cells to Understand Disease Processes and Study New Treatments Going Viral to Target Tumors Researchers Identify Genes That Appear to Predict Tumors That Can Evade Detection by Immune System Stem Cell Advance Yields Mature Heart Muscle Cells Motion-Sensing Cells in the Eye Let the Brain ‘Know’ About Directional Changes How Cancer Cells Metastasize Into Brain Tumors Novel Technique for Cell Lineage-Specific Gene-Expression Analysis Cancer Vaccine Could Use Immune System to Fight Tumors Team Discovers Stem Cells in the Esophagus—Could Lead to New Models to Study Esophageal Disease Creating Medical Devices with Dissolving Metal Pitt School of Dental Medicine Team Awarded $2 Million NCI Grant to Study How Cancer Spreads to Bone Pitt Gets $11 Million from NIH to Lead Center of Excellence in National Big Data Research Consortium Pittsburgh Pediatric Mechanical Cardiopulmonary Support Reaches to Florida $1.25 Million Received from Defense Department to Make Whole-Eye Transplantation a Reality New Processes Could Provide Personalized Pain Treatment Unraveling Traumatic Brain Injuries UPMC Voice Center: A Unique Resource Dr. Andrew Duncan Receives NIH Grant Focused on Obtaining a Better Understanding of Liver Biology Pitt, Carnegie Mellon Engineers Develop New Method to Explore Mechanical Communication Between Cells Needle Treatment for Glaucoma Shows Promise: A Monthly Injection That Might Replace Eye Drops Used Twice Daily Dr. John Kellum Helps Develop New Kidney Test Genetic Discovery Yields Prostate Cancer Test, Promise of Future Therapy Dr. Keith Cook to Develop Artificial Lungs that Can Be Worn at Home Study Findings Could Lead to Improved Treatments for Stroke, Other Brain Injuries Dr. Ipsita Banerjee Receives NSF Grant Older Adults with Depression and Mild Cognitive Impairment Are More Vulnerable to Accelerated Brain Aging Pitt/Industry Partnership Helps Students Develop Ideas and Products Surgical Adhesive Technology Receives FDA Panel Recommendation Clinical Imaging in Regenerative Medicine McGowan Institute for Regenerative Medicine Collaborators Create Nanofibers Using Unprecedented New Method Surgical, Other Advances Improve Graft Survival of Intestinal, Multi-Visceral Transplant Patients First “Regenerative Medicine Summer School” Week The Charles E. Kaufman Foundation Awards Funds to McGowan Institute Affiliated Faculty for Scientific Studies Study Suggests Cystic Fibrosis is Two Diseases, One Doesn’t Affect Lungs Research Sheds Light on Nerve Regeneration Following Spinal Cord Injury First Class 1 Evidence for Cognitive Rehabilitation in MS Therapy Using Stem Cells, Bone Marrow Cells, Appears Safe for Patients with Ischemic Cardiomyopathy Protein Shed by HIV-Infected Brain Cells Alters Synaptic Connections Between Networks of Nerve Cells Deletion of Any Single Gene Provokes Mutations Elsewhere in the Genome Study Shows Decrease in Sepsis Mortality Rates Gut Microbes in Healthy Kids Carry Antibiotic Resistance Genes Healthy Stem Cells Can Create Benign Tumors in Jaw, USC Study Finds How Body Clock Affects Inflammation: Discovery Could Accelerate Body's Response to Infection, Autoimmune Disorders New Strategy Could Uncover Genes at the Root of Psychiatric Illnesses ‘Master Switch’ For Myelination in Human Brain Stem Cells Is Identified American Academy of Ophthalmology Does Not Recommend Marijuana for Glaucoma Treatment Notorious Pathogen Forms Slimy 'Streamers' to Clog Up Medical Devices Immune Cells Found to Prevent Bone Marrow Transplant Rejection New Study Advances Safety, Efficacy Profile of Virus-Specific T Cells for Post-Transplant Recipients NSF Funding For Nanotechnology Bladder Cancer Detection Device Sensor in Eye Could Track Pressure Changes, Monitor for Glaucoma Biologists Find 'Missing Link' in the Production of Protein Factories in Cells Scientists Identify Link Between Stem Cell Regulation and the Development of Lung Cancer Vaccine 'Reprograms' Pancreatic Cancers to Respond to Immunotherapy Gut Bacteria Predict Survival after Stem Cell Transplant, Study Shows Stem Cells in Neurodegeneration: Challenges and Future Neurotherapeutic Prospects Penn Study Describes New Models for Testing Parkinson's Disease Immune-Based Drugs Embryonic Stem Cells Offer Treatment Promise for Multiple Sclerosis Insulin's Risks as Second-Line Medicine to Treat Type 2 Diabetes Dormant Viruses Re-Emerge in Patients with Lingering Sepsis, Signaling Immune Suppression Viral Infections, Including Flu, Could Be Inhibited by Naturally Occurring Protein MRI Brain Scans Detect People with Early Parkinson's TB Dogma Upended: Even Uninfected Cells Trigger Immune Defenses Researchers Use Human Stem Cells to Create Light-Sensitive Retina in a Dish Scientists Use Stem Cells to Create HIV Resistance Protein That Keeps Blood Stem Cells Healthy as They Age Identified by Researchers Nanotechnology Researchers Develop 'Onion' Vesicles for Drug Delivery Fasting Triggers Stem Cell Regeneration of Damaged, Old Immune System Making Artificial Vision Look More Natural Short Nanotubes Target Pancreatic Cancer Transplanted Fetal Stem Cells for Parkinson's Show Promise Four New Genes Confirmed to Increase Familial Breast Cancer Risk Coaxing iPS Cells to Become More Specialized Prior to Transplantation Cuts Rejection Risk, Study Shows For the First Time in the Lab, Researchers See Stem Cells Take Key Step Toward Development Findings Have Important Implications for Improving War Wound Healing Researchers Use Light to Coax Stem Cells to Repair Teeth Naturally Occurring Antibodies May Be Treatment for BK Nephropathy in Kidney Transplant Patients From Stem Cells, New Roots Pitt Researchers Receive $2.1 Million to Study Prevention of Deadly Lung Injury Stem Cells Hold Keys to Body's Plan Gene Therapy Combined with IMRT Found to Reduce Recurrence for Select Prostate Cancer Patients Neuron Tells Stem Cells to Grow New Neurons Stem Cell Therapy May Help Recondition Lungs Previously Rejected for Transplant Team Highlights New Mechanism Explaining How Cancer Cells Spread Scientists Discover Potential New Target for Cancer Immunotherapy DNA Nanotechnology Places Enzyme Catalysis Within an Arm's Length Study Identifies How Signals Trigger Cancer Cells to Spread Researchers Profile Active Genes in Neurons Based on Connections Watching HIV Bud from Cells: Study Shows Last-Minute Role of Protein Named ALIX Pitt Study Shows for First Time How Huntington’s Disease Protein Could Cause Death of Neurons New Study Identifies Heart-Specific Protein That Protects Against Arrhythmia Breakthrough in HIV/AIDS Research Gives Hope for Improved Drug Therapy Herpes-Loaded Stem Cells Used to Kill Brain Tumors B Cells Produce Antibodies 'When Danger Calls, But Not When it Whispers,' Scientists Report Ophthalmology Studies Focus on Glaucoma Medication Adherence Enzyme Helps Stem Cells Improve Recovery from Limb Injuries An Eye Toward Better Treatment BYU Researchers Create Tiny Nano-Device in Newest Gene Therapy Advance Engineers Fabricate Microscale Silk Proteins Patterns for Use in Tissue Engineering and 'Green Devices' Potential Therapeutic Target for Wound-Healing and Cancer Identified Patient Stem Cells Used to Make 'Heart Disease-on-a-Chip' New Nanotechnology Method Sneaks Drugs into Cancer Cells Before Triggering Release NIH Study Demonstrates That a New Cancer Immunotherapy Method Could Be Effective Against a Wide Range of Cancers Scientists Decode Epigenetic Mechanisms Distinguishing Stem Cell Function and Blood Cancer Ovarian Cancer Cells Are More Aggressive on Soft Tissues Spurt of Heart Muscle Cell Division Seen in Mice Well After Birth: Implications for Repair of Congenital Heart Defects Study Confirms Clinical Benefit for Interleukin-2 Immunotherapy in Patients with Advanced Kidney Cancer Stem Cells Could Be the Answer for Treating Fecal Incontinence After Injury or Disease Discovery Helps Explain How B Cells Adapt to Their Targets A Transcription Factor Called SLUG Helps Determines Type of Breast Cancer Human Fat: A Trojan Horse to Fight Brain Cancer? Technology Developed by McGowan Faculty Permitted the First U.S. Implant of a Medical Device Before Lifesaving Double Lung Transplant Pitt’s Center for Medical Innovation Awards 2014 Round-1 Pilot Funding Deep Brain Stimulation for Parkinson’s Disease Mouse Study Offers New Clues to Cognitive Decline Mitochondrial Deficits in Children with Autism Confirmed Universal Neuromuscular Training an Inexpensive, Effective Way to Reduce ACL Injuries in Athletes Physicists Working to Cure 'Dry Eye' Disease Researchers Identify How Heart Stem Cells Orchestrate Regeneration Reijo Pera and Team: Stem Cell Research Holds Promise for Male Infertility Brain Tumor Cells Penetrated by Degradable Nanoparticles Carrying Genetic Instructions Overlooked Cells Hold Keys to Brain Organization and Disease A Civil War Inside Our Cells: Scientists Show How Our Bodies Fight Off 'Jumping Genes' Cells Are More Resilient Than Originally Thought, Say Scientists Bio-Engineers Grow Functional Human Cartilage in Vitro Team Reprograms Blood Cells into Blood Stem Cells in Mice Stem Cells in Circulating Blood Affect Cardiovascular Health, Study Finds Nanotechnology Researchers Demonstrate Potential of RNA as Heat-Resistant Polymer Material for Nanoarchitectures Cancer Stem Cells Linked to Drug Resistance Researchers Discover How Intestinal Cells Build Nutrient-Absorbing Surface Some Immune Cells Defend Only One Organ Engineering Cell-Based, Biological Devices May Selectively Kill Cancer Cells Without Disrupting Healthy Cells Hydrogen Sulfide Regulates Bone Marrow Mesenchymal Stem Cells, Shows Study $2.9 Million Grant to Improve Brain Implants Received McGowan Institute Medical Device Technology Receives Gold Medical Design Excellence Award Efficient Analysis of Small Quantity of Cells Improves Chances to Understand Disease Engineers Help Make Advances in Virtual Artificial Heart Implantation Discovery Could Have Far-Reaching Implications for Diagnosis and Treatment of Diabetic Retinopathy Research Reveals Evolution of Cells' Signaling Networks in Diverse Organisms Modified Stem Cells Offer Potential Pathway to Treat Alzheimer's Disease New Technique of Single-Cell Genomic Analysis to Reverse Tissue Engineering New Method Isolates Immune Cells for Researchers to Study How They Ward Off Oral Diseases Nanotechnology Unlocks New Pathways for Targeted Drug Delivery How a Silly Putty Ingredient Could Advance Stem Cell Therapies Laboratory-Grown Vaginas Implanted in Patients, Scientists Report Dr. Anna Balazs’ Work Featured on the Cover of Journal of Physical Chemistry Letters Dr. Juan Carlos Puyana to Share $1.6M Grant Team Solves Decades-Old Mystery of How Cells Keep From Bursting Surface-Modified Nanocellulose Hydrogels for Wound Dressing Researchers Identify Transcription Factors Distinguishing Glioblastoma Stem Cells Too Much Protein May Kill Brain Cells as Parkinson's Progresses Detecting Infection with a Microchip Researchers Show How Cancer Cells May Respond to Mechanical Force Bone Marrow Stem Cells Show Promise in Stroke Treatment Study Provides Insights into Why Alcohol Has Negative Effect on Wound Healing Researchers Develop Technique to Measure Quantity, Risks of Engineered Nanomaterials Delivered to Cells Tumor Suppressor Gene Linked to Stem Cell Function Some Breast Cancer Tumors Hijack Patient Epigenetic Machinery to Evade Drug Therapy Stem Cell-Derived Beta Cells Under Skin Replace Insulin First Stem Cell Study of Bipolar Disorder Yields Promising Results Stem Cell Findings May Offer Answers for Some Bladder Defects and Disease A New Way to Make Muscle Cells from Human Stem Cells Proteins That Control Energy Use Necessary to Form Stem Cells Study Identifies DNA Region Linked to Severity of Herpes Simplex Infections Study Finds Stem Cell Combination Therapy Improves Traumatic Brain Injury Outcomes Study Finds That Fast-Moving Cells in the Human Immune System Walk in a Stepwise Manner Department of Defense Peer Reviewed Medical Research Program Funding Received Regenerative Medicine Improves Muscle Strength and Function in Leg Injuries Cartilage, Made to Order: Living Human Cartilage Grown on a Lab Chip Non-Invasive Imaging of the In Situ Restoration of Brain Tissue Malfunction in Molecular ‘Proofreader’ Prevents Repair of UV-Induced DNA Damage Metabolic Profiling of Liver Cells Suggests New Treatments for Cirrhosis Patients Key Heart Failure Culprit Discovered in Tiny Piece of RNA Finding Hiding Place of Virus Could Lead to New Treatments Stem Cell Study Opens Door to Undiscovered World of Biology Aged Mice Lacking Antioxidant Protein Nrf2 Show Poor Stem Cell Regeneration Diabetes Researchers Track Cells' Ability to Regenerate UV Light Accelerates Cancer Cells That Creep Along the Outside of Blood Vessels Cellular Alchemy: How to Make Insulin-Producing Cells from Gut Cells Using Nanotechnology to Improve the Speed, Efficiency, and Sensitivity of Biosensors Alzheimer’s in a Dish Tumor Cells - Finding a Few Foes Among Billions of Cellular Friends Nanoparticles and Magnetic Fields Train Immune Cells to Fight Cancer in Mice Scientists Transform Skin Cells Into Functioning Liver Cells New Nanotechnology Method to Fight Cancer with Tissue-Penetrating Light High-Calorie Diet Could Slow Progression of Motor Neuron Disease (ALS), Study Finds Watching How the Brain Works With New Live Imaging First Look at How Individual Staphylococcus Cells Adhere to Nanostructures Could Lead to New Ways to Thwart Infections Imaging Dynamics of Small Biomolecules Inside Live Cells It Slices, It Dices, and It Protects the Body from Harm: 3-D Structure of Enzyme That Helps Defend Against Bacteria Promising Results with Local Hyperthermia of Tumors Prenatal Nicotine Exposure May Lead to ADHD in Future Generations Fragile X Syndrome: Trigger For Most Common Form of Intellectual Disability and Autism Uncovered Novel Therapeutic Targets for Huntington's Disease Discovered Causal Link Found Between Vitamin D, Serotonin Synthesis, and Autism in New Study New Clues Found to Prevent Lung Transplant Rejection Animal Cells Can Communicate by Reaching Out and Touching, Team Discovers Two Players Produce Destructive Cascade of Diabetic Retinopathy Designer 'Swiss-Army-Knife' Molecule Captures RNA in Single Cells in Their Natural Tissue Environment Study Identifies Population of Stem-Like Cells Where HIV Persists in Spite of Treatment Red Blood Cells Take on Many-Sided Shape During Clotting Harvard Scientists Control Cells Following Transplantation, From the Inside Out Stem Cell Research Identifies New Gene Targets in Patients with Alzheimer's Disease Color-Coded Cells Reveal Patchwork Patterns of X Chromosome Silencing in Female Brains Stem Cells Used to Model Disease That Causes Abnormal Bone Growth Scientists Make Living Brain Cells from Alzheimer's Patients Biobanked Brain Tissue Biomaterials Get Stem Cells to Commit to a Bony Future Researchers Target Cancer Stem Cells in Malignant Brain Tumors Researchers Gain Insight Into Retinal Detachment After Open Globe Injury Biologists Discover Solution to Problem Limiting Development of Human Stem Cell Therapies Study Finds Patients Give “Broad Endorsement” to Stem Cell Research Novel Noninvasive Therapy Prevents Breast Cancer Formation in Mice Researchers Fast-Forward Stem Cell Aging to Study Degenerative Diseases Tufts Researchers Identify Potential Topical Treatment for Macular Degeneration Platelet-Rich Plasma and Fat Grafting: An Option? Model-Based Decisions in Sepsis (MODS) The Whole Liver Replacement State-of-the-Science Summit Integrating Mental Health Services in Pediatric Practices Feasible, Effective, Pitt Finds Lifestyle Interventions Can Prevent Major Depression in Older Black and White Adults with Mild Symptoms Designing Better Vascular Grafts Turing’s Theory of Morphogenesis Validated 60 Years After His Death Exploring 3-D-Printed Bone and Tissue Scaffolds Pitt/MWRI Researchers Awarded Prestigious Cozzarelli Prize for Top Biomedical Sciences PNAS Paper of 2013 Study Challenges Accepted Sepsis Treatment Stem Cells from Muscle Can Repair Nerve Damage After Injury Lizards May Answer Cartilage Regeneration Mystery Biomarkers That Can Provide Advance Warning of Deadly Kidney Condition in Critically Ill Patients Identified Innovative Brain Imaging Technology Receives DSF Charitable Foundation Funding Autophagy Predicts Which Cancer Cells Live and Die When Faced With Anti-Cancer Drugs Draper Nanotechnology Could Fight Influenza, Other Viruses Stimulating Brain Cells Stops Binge Drinking, Animal Study Finds Gene Therapy Method Targets Tumor Blood Vessels Common Disorders: It’s Not the Genes Themselves, But How They Are Controlled Adult Stem Cells Found to Suppress Cancer While Dormant New Data for Engineering Immune Cells Shows Promise in Solid Tumors Early Detection of Blinding Eye Disease Could be as Easy as Scanning a Barcode New - and Reversible - Cause of Aging: Naturally Produced Compound Rewinds Aspects of Age-Related Demise in Mice How Cells Remodel After UV Radiation Researchers Generate Kidney Tubular Cells From Stem Cells Scientists Discover How Immune Cells Die During HIV Infection; Identify Potential Drug to Block AIDS Mouse Study Shows Potential for Gene Therapy in Alport Syndrome, an Inherited Kidney Disease Stem Cells Offer Clues to Reversing Receding Hairlines Microprinting Leads to Low-Cost Artificial Cells New Delivery Vehicle Developed For Gene Therapy Stem Cell Research Uncovers Importance of Cell Cycle Activated “Killer” T-Cells Effective Against Resistant Lymphoma Lung Lesions of TB Variable, Independent Whether Infection is Active or Latent, Says Pitt Study Team Finds Potential Treatment for Skin and Corneal Wound Healing in Diabetics UCLA Stem Cell Researchers Track Early Development of Human Articular Cartilage Salmonella Jams Signals From Bacteria-Fighting Mast Cells Tumor-Suppressing Genes Could Play Important Role in Obesity, Diabetes, and Cancer Brain Cancer Cells Hide While Drugs Seek Type 1 Diabetes: A Treatment's in Sight? Precise Electronic Drug Release Thanks to Graphene Oxide Nanocomposite Material Small Blood Pumps for Small Patients Funding Awards for New Biomedical Technology Announced Mood-Stabilizing Drug Could Be New Treatment for Inherited Liver Disease Pioneering Initiative = Improved Standard of Care + Educational Success Pitt Establishes Brain Institute to Unlock Mysteries of the Brain, Discover Novel Therapies Pennsylvania’s First Minimally Invasive Heart Pump Implant New Research Implicates Immune System Cells in Muscle Healing New Gene Therapy Targets Hemophilia Brain's Never-Before-Seen Cellular Response to Concussions Could Lead to Therapy Study Finds Biomaterials Repair Human Heart New Sensor Tracks Zinc in Cells Tiny Oil Droplets Help Measure Mechanical Forces Produced by Living Cells That Shape Tissues and Organs New Drug Approach Could Lead to Cures for Wide Range of Diseases Innovative Contact Lens Delivers Glaucoma Medication Continuously PKM2 Protein Controls Mitosis, Saving Cancer Cells from Death and Promoting Brain Tumor Growth Staying Ahead of Huntington's Disease Activating Pathway Could Restart Hair Growth in Dormant Hair Follicles, Penn Study Suggests Gene Therapy Bolsters Enzyme Activity to Combat Alzheimer's Disease in Mice Researchers Discover Early Step in Blood Stem Cell Development Researchers Unlock a New Means of Growing Intestinal Stem Cells Human Stem Cells Converted to Functional Lung Cells Scientists Discover How Leukemia Cells Exploit 'Enhancer' DNA Elements to Cause Lethal Disease Researchers Identify Cells Involved in Placenta Development Nanotechnology Improves Cardiovascular Implant Attachment Researchers at Penn Uncover Mechanism Behind Blood Stem Cells’ Longevity How Living Cells Solved a Needle in a Haystack Problem to Produce Electrical Signals Gene-Silencing Study Finds New Targets for Parkinson's Disease NIH Mouse Study Finds Gut Microorganisms May Determine Cancer Treatment Outcome B Cells School Gut Microbes Newly Identified Brown Fat Stem Cells Hold Possibilities for Treating Diabetes, Obesity Nanotechnology Technique May Help Diabetics Avoid the Needle Rare Disease Yields Clues About Broader Brain Pathology 'Mini-Kidney' Structures Generated from Human Stem Cells for First Time Drug Shows Early Promise in Treating Seizures Mitochondrial Mystery: Investigating Cells' Power Packs Fuels Understanding of Rare, and Common, Diseases Persistent Gene Therapy in Muscle May Not Require Immunosuppression Understanding a Protein's Role in Familial Alzheimer's Disease New Trigger for Breast Cancer Metastasis Identified Determining Acute Kidney Injury Pitt Study Finds Mechanism for Increased Activity of Oncogene in Head and Neck Cancers Pitt Researchers to Study New Treatments for Pancreatic Cancer Patients Novel Biological Sources for Battery Materials Ballet and Sports Medicine Personalized Medicine for Pancreatic Diseases Regenerative Medicine Partnership with Cornell University New “Zero-Dimensional” Carbon Nanotube May Lead to Superthin Electronics and Synthetic Cells Muscle Morbidity and Reduced Regenerative Capacity Human Stem Cells Used to Reveal Mechanisms of Beta-Cell Failure in Diabetes New Treatment Discovered to Cure MRSA Infection Novel Gene Therapy Works to Reverse Heart Failure Nanotechnology Researchers Prove Two-Step Method for Potential Pancreatic Cancer Treatment Finding Antitumor T Cells in a Patient's Own Cancer Signal Found to Enhance Survival of New Brain Cells Drug Combination Therapy Causes Cancer Cells to 'Eat Themselves' Stem Cells Linked to Cognitive Gain After Brain Injury in Preclinical Study Novel Nanotechnology Therapeutics Silences Incurable Brain Cancer Gene NIH Funds Researchers Using Light to Control and Monitor Neural Activity Effects of Chronic Stress Can Be Traced to Your Genes Study Finds Molecular Link Between Gut Microbes and Intestinal Health NEJM Study Evaluates Early Stem Cell Transplants For Non-Hodgkin's Lymphoma Researchers Identify Way to Increase Gene Therapy Success Zebrafish Useful Tool in Prostate Cancer Stem Cell Study Yeast, Human Stem Cells Drive Discovery of New Parkinson's Disease Drug Targets Researchers Apply Brainpower to Understanding Neural Stem Cell Differentiation Bioinformatics Breakthrough: High Quality Transcriptome from as Few as Fifty Cells Promising Technique for Treating Eye Disease Proves Effective in Preclinical Studies A New Model For Organ Repair: Kidney Repair May Not Require Stem Cells Proposed: New Composites That Can Regenerate When Damaged Pitt Team Aims to Change Tissue Microenvironment to Fend Off Cancerous Tumors Multicenter, Multidisciplinary Effort to Study Hemorrhaging in Trauma Patients Sensory Substitution Helps the Blind See Compounded Medication to Prevent Preterm Birth Not a Safety Risk Weighing In: Three Years Post-Op Bariatric Surgery Patients See Big Benefits Insights Into Genetic Architecture of OCD, Tourette Syndrome Grafted Limb Cells Acquire Molecular 'Fingerprint' of New Location, Study Shows No Evidence to Support Stem Cell Therapy For Pediatric Optic Nerve Hypoplasia Cells' 'Molecular Muscles' Help Them Sense and Respond to Their Environments Physical Cues Help Mature Cells Revert Into Embryonic-Like Stem Cells Complex Diseases Traced to Gene Copy Numbers Nanotechnology Ovarian Cancer Treatment Succeeds in the Lab Hardening of Arteries in Elderly Adults Linked to Plaques in Brain, Pitt Study Finds Team Takes First Step Toward Macular Dystrophy Gene Therapy Lou Gehrig’s Disease: From Patient Stem Cells to Potential Treatment Strategy Nanotech System, Cellular Heating May Improve Treatment of Ovarian Cancer Elusive Secret of HIV Long-Term Immunity Brain Scans May Aid in Diagnosis of Autism Separating the Good from the Bad in Bacteria ‘Individualized’ Therapy for the Brain Targets Specific Gene Mutations Causing Dementia and ALS New Evidence That Aging Tumor Cells May Be an Effective Cancer Treatment Adult Stem Cells Help Build Human Blood Vessels in Engineered Tissues Database of Disease Genes Shows Potential Drug Therapies Outside Influence: Genes Outside Nucleus Have Disproportionate Effect Stomach Cells Naturally Revert to Stem Cells In Stem Cells, Like Real Estate, Location is Most Important Factor Burn Therapy: An Award-Winning Regenerative Medicine Approach Innate Virus-Killing Power Discovered in Mammals Loss of Anti-Aging Gene Possible Culprit in Age-Related Macular Degeneration Newly Discovered Gene Regulator Could Precisely Target Sickle Cell Disease Genes Protect Themselves Against Being Silenced Single Gene Mutation Linked to Diverse Neurological Disorders Awakening Genes That Suppress Tumors Retinitis Pigmentosa Test Identifies Mutation Found in Ashkenazi Jewish Population Researchers Find Six New Sjogren's Syndrome Genes Cells Prefer Nanodiscs Over Nanorods How JC Polyomavirus Invades Cells Creating 'Re-Specified' Stem Cells for Disease Modeling Gum Disease Treated by Using Homing Beacon to Bring Needed Immune Cells to Inflamed Area Traumatic Brain Injury Research Advances with $18.8M NIH Award Improving the Therapeutic Relevance of Muscle Stem Cells Nano-Dissection Identifies Genes Involved in Kidney Disease Researchers Uncover Keys to Antibiotic Resistance in MRSA Stem Cells Engineered to Become Targeted Drug Factories Scientists Identify 140 Regions of Genetic Code Believed to Contain Undiscovered Cancer Genes Important Wound-Healing Process Discovered Sister Stem Cells Display Considerable Differences Despite Having Identical DNA Novel Drug Prevents Common Viral Disease in Stem-Cell Transplant Patients, Study Finds Setting Blurred Images in Motion Improves Perception iPhones for the Eyes: Smart Phone Photography to Help Diagnose Eye Disease Blocking Nerve Cells Could Prevent Symptoms of Eczema Cell Powerhouses Shape Risk of Heart Disease Cancer Cells Propagated From Early Prostate Cancer Model Developed for Studying Tissue Pattern Formation During Embryonic Development New Approach to Treating Human Brain Cancer Could Lead to Improved Outcomes Nanoparticle Vaccine: Particles That Deliver Vaccines Directly to Mucosal Surfaces Could Defend Against Many Infectious Diseases Genetic Makeup and Diet Interact With the Microbiome to Impact Health Model to Study Human Response to Bacteria That Cause Peptic Ulcers Developed Cancer-Killing Cells Controlled by Epigenetic Process, New Study Shows Signal Gradients in 3-D Guide Stem Cell Behavior Whole DNA Sequencing Reveals Mutations, New Gene for Blinding Disease Depletion of ‘Traitor’ Immune Cells Slows Cancer Growth in Mice 'Wildly Heterogeneous Genes' ‘Vicious Cycle’ Shields, Spreads Cancer Cells Researchers Use New Genetic Mapping Technique to Identify Two Genes That Can Cause Vision Loss in Seniors Faulty Stem Cell Regulation May Contribute to Cognitive Deficits Associated With Down Syndrome Stem Cell Transplants May Be a Novel Treatment for Schizophrenia Research Points to Promising Treatment for Macular Degeneration Strategic Partnership in Regenerative Medicine Formed With Instron Study Indicates Benefits of Stem Cells in Treating MS Declines With Donor’s Age Scientist Identifies Helper Cells That Trigger Potent Responses to HIV Finding Could Potentially Make iPS Cells Safer For Use in Humans Sleep Boosts Production of Brain Support Cells Scientists Pinpoint 105 Additional Genetic Errors That Cause Cystic Fibrosis Unprecedented Control of Genome Editing in Flies Promises Insight Into Human Development, Disease Aggressive Lymphoma: Low Doses of Approved Drug Switches on Pathway That Allows Chemotherapy to Kill Cancer Pitt Scientists Solve Mystery of Basic Cellular Process Entering a New Dimension: 4D Printing Drs. Rubin and Marra Comment on Denmark Stem Cell-Enriched Fat Grafts Clinical Study The Latest Advances in Technology for People with Spinal Cord Injury NSF Grant Explores “Materials That Compute” Novel Therapeutic Cancer Vaccine Goes to Human Clinical Trials Cell Death Protein Could Offer New Anti-Inflammatory Drug Target First Detailed View of Morphing Parkinson's Protein Revealed Scientists Link a Protein to Initial Tumor Growth in Several Cancers Study Examines Ways to Restore Immunity to Chronic Hepatitis C Infection Molecular Beacons Light Path to Cardiac Muscle Repair An Easier Way to Control Genes Proteins in Histone Group Might Influence Cancer Development, Study Shows New Imaging Technology Promising For Several Types of Cancer Protein That Protects Nucleus Also Regulates Stem Cell Differentiation Scripps Florida Scientists Detail Critical Role of Gene in Many Lung Cancer Cases Scientists Identify Amyotrophic Lateral Sclerosis Disease Mechanism Blocking Molecular Pathway Reverses Pulmonary Hypertension in Rats Model of 'Near-Optimal' Genetic Code Developed Key Enzymes Are Found to Have a 'Profound Effect' Across Dozens of Genes Linked to Autism Butterfly Wings + Carbon Nanotubes = New 'Nanobiocomposite' Material Team 'Spikes' Stem Cells to Generate Myelin A Major Cause of Age-Related Memory Loss Identified: Potentially Reversible Stem Cells May Do Best With a Little Help From Their Friends Hodgkin Lymphoma Treatment Linked to Possible Risk of Stomach Cancer Disabling Enzyme Reduces Tumor Growth, Cripples Cancer Cells, Study Finds Harmonizing a Broken Heart: Stem Cells Keep Cardiac Beat in Synchrony Scientists Uncover How Superbug Fights Off Antibiotic Third Annual Regenerative Rehabilitation Symposium, April 10-11, 2014, San Francisco, California McGowan Institute for Regenerative Medicine to Co-Direct $75 Million Second Phase of National Effort to Aid Wounded Warriors Unusual Combination Therapy Shows Promise for Preventing Prostate Cancer Receptor May Aid Spread of Alzheimer's and Parkinson's in Brain Fetal Stem Cell Transplantation Favorably Impacts Radiation-Induced Cognitive Dysfunction Team Creates Cells That Line Blood Vessels University of Hawaii Cancer Center Researcher Identifies Association Between Healthy Diet and Reduced Risk of Bladder Cancer Therapeutic Eye Injections May Be Needed Less Often Dialing Back Treg Cell Function Boosts Cancer-Fighting Immune Activity Researchers Transform Fluorescent Proteins Into a Scaffold For Manipulating Genes Van Andel Institute Discovery Could Help Diagnose Precursor to Pancreatic Cancer Risk of Dementia Doubles for Elderly Patients Hospitalized with Infections Artificial Cells to Study Effects of Molecular Crowding on Gene Expression Developed Mending a Broken Heart? Scientists Transform Non-Beating Human Cells Into Heart-Muscle Cells Study Helps Explain Increased Risk of Melanoma in People with Red Hair Bacteria Make Us Feel Pain ... and Suppress Our Immune Response In Regenerating Planarians, Muscle Cells Provide More Than Heavy Lifting FDA Approves MSC-NP Therapy as Investigational New Drug in MS Clinical Trial: A Research Milestone Six Months of Fish Oil Reverses Liver Disease in Children with Intestinal Failure, Study Shows New Gene Repair Technique Promises Advances in Regenerative Medicine Rules Governing Expression of Developmental Genes in Mouse Embryonic Stem Cells Are More Nuanced Than Anticipated Nanodrug Targeting Breast Cancer Cells from the Inside Adds Weapon: Immune System Attack Burkitt Lymphoma Survival Improves For Some Helper Cells Aptly Named in Battle with Invading Pathogens Gene Regulator is Key to Healthy Retinal Development and Good Vision in Adulthood Researchers Report a Critical Role for the Complement System in Early Macular Degeneration Writing Rules for Gene-Therapy Vectors: Researchers Compute, Then Combine Benign Viruses to Fight Disease Study Finds New Genes Behind Severe Childhood Epilepsy New Evidence That Cancer Cells Change While Moving Throughout Body Scientists Identify Biomarker to Predict Immune Response Risk After Stem Cell Transplants Type 1 Diabetes Drug Strikingly Effective in Clinical Trial Mechanism That Allows Bacteria to Infect Plants May Inspire Cure for Eye Disease Gut Reaction: Mice Survive Lethal Doses of Chemotherapy Dad's Genes Build Placentas, Study Shows NIH Scientists Visualize How Cancer Chromosome Abnormalities Form in Living Cells Researchers Adapt Microscopic Technology for Bionic Body Parts and Other Medical Devices Making Connections in the Eye: Wiring Diagram of Retinal Neurons is First Step Toward Mapping the Human Brain Stem Cells Found in Gum Tissue Can Fight Inflammatory Disease Study Reveals Genes That Drive Brain Cancer More Intestinal Cells Can Absorb Larger Particles Ultrasound Patch Heals Venous Ulcers in Human Trial UC San Diego Researchers Develop Efficient Model for Generating Human iPSCs Study Findings Offer a Promising New Direction for Organ Regeneration and Tissue Repair Long-Sought Method to Efficiently Make Complex Anticancer Compound Developed New Treatment Strategy for Breast Cancer Spread to Brain Advance in Regenerative Medicine Could Make Reprogrammed Cells Safer While Improving Their Function Burnt Sugar Derivative Reduces Muscle Wasting in Fly and Mouse Muscular Dystrophy UPCI Researchers Target ‘Cell Sleep’ to Lower Chances of Cancer Recurrence Genetics: More Than Merely a Mutated Gene Inhalable Gene Therapy May Restore Function of Crucial Enzyme to Reverse Deadly PAH Neuroscience Professor Links Diet Deficits to Hyperactivity in Teens Stimulating Brain Cells Can Make False Memories NIH Researchers Discover How Brain Cells Change Their Tune Effects of Purging Tumor Cells from Stem Cells in Patients Transplanted For High-Risk Neuroblastoma Target for Drug Development for Chronic Jaw Pain Disorder Revealed Reprogramming Patients' Cells Offers Powerful New Tool for Studying, Treating Blood Diseases Silky Brain Implants May Help Stop Spread of Epilepsy Stem Cell-Based Epilepsy Approach May Help in Search for Better Medicines to Treat Seizure Disorders Scientists Reach the Holy Grail in Label-Free Cancer Marker Detection: Single Molecules A New Weapon Against Stroke Gene Therapy for Type 1 Diabetes Aims to Eliminate Daily Insulin Injections A Flip of the Mitotic Spindle Has Disastrous Consequences for Epithelial Cells Controlling Genes With Light Researchers Step Closer to Custom-Building New Blood Vessels Decellularized Mouse Heart Beats Again after Regeneration with Human Heart Precursor Cells University of Pittsburgh Cancer Institute International Academy Scholars Present Projects Coulter Foundation Translational Research Partnership Program Invests in 3 Medical Technologies of McGowan Institute for Regenerative Medicine Affiliated Faculty Practice Makes the Brain’s Motor Cortex More Efficient Light That Moves and Molds Gels Premature Aging of Immune Cells Present in Joints of Kids with Chronic Arthritis NIH Grant to Study Pediatric Traumatic Brain Injuries Received Genetic Glitch at the Root of Allergies Revealed Key Molecular Pathways Leading to Alzheimer's Identified New Research Suggests That Gingival Stem Cells Can be Used in Tissue Regeneration CHOP-Led Research Increases Numbers of Patients Who Could Be Treated with Gene Therapy Scientists Show Proof-of-Principle for Silencing Extra Chromosome Responsible for Down Syndrome Researchers Generate Long-Lasting Blood Vessels from Reprogrammed Human Cells Recycling in the Eye Promotes Good Vision Successful Restoration of Hearing and Balance A Secret to Making Macrophages Gene Mutation Linked to Obesity: Mice Gain Weight Even When Fed Normal Amounts of Food Gold Nanofibers in Engineered Heart Tissue Can Enhance Electrical Signaling Poor Sleep in Pregnancy Can Disrupt the Immune System and Cause Birth-Related Complications, Pitt Study Finds Steering Stem Cells With Magnets: Proof of Concept For Clinical Applications Nanotechnology Drug Crosses Blood-Brain Tumor Barrier, Targets Brain Tumor Cells Interspecies Transplant Works in First Step For New Diabetes Therapy Injecting Iron Supplement Lets Scientists Track Transplanted Stem Cells UNMC Nanotechnology Protects Skin from Cancer and Early Wrinkles Researchers Perform DNA Computation in Living Cells Cell Therapy May Overcome Major Challenges in Organ Transplantations Microparticles Create Localized Control of Stem Cell Differentiation Stem-Cell Therapy for Treatment of Stroke Has Benefits as Well as Risk Nanotechnology Approach Could Lead to 'Artificial Skin' That Senses Touch, Humidity, and Temperature Plant-Made Drug Reverses Breathing Paralysis, Study Suggests Unique Epigenomic Code Identified During Human Brain Development New Approaches to Understanding Infection May Uncover Novel Therapies Against Influenza McGowan Institute for Regenerative Medicine Affiliated Faculty Members Receive Project Funding for Early Stage Medical Technology R&D Artificial Cells to Study Effects of Molecular Crowding on Gene Expression Developed Placental Cells May Prevent Viruses from Passing from Mother to Baby Biomarker Predicts Heart Attack Risk Based on Response to Aspirin Therapy Clues About Autism May Come From the Gut Dissecting the Distinctive Walk of Disease UCLA Stem Cell Gene Therapy For Sickle Cell Disease Advances Toward Clinical Trials Nerve Cells Can Work in Different Ways with Same Result, Says MU Researcher Mimicking Living Cells: Synthesizing Ribosomes A Telescope For the Eye: New Contacts May Improve Sight For Macular Degeneration Patients Researchers Strike Gold With Nanotechnology Vaccine Results of Landmark 11-Year Study on Weight Loss’s Effect on Heart Disease Risks Published Genes Involved in Birth Defects May Also Lead to Mental Illness Study Sets Guidelines for Stem Cell Transplants in Older Patients with Myelodysplastic Syndromes Nanotechnology Sensor Shows Promise to Detect Disease With Drop of Blood Scientists Use Stem-Cell Technology to Create Research Cell Line From PDAC Patient Stem Cell Patterns in Flies Offer Potential Applications For Human Biologists Research Uncovers Approach That May Decrease Complications of Stem Cell Transplants for Cancer NYSCF and Columbia Researchers Demonstrate Use of Stem Cells to Analyze Causes and Treatment of Diabetes Fingernails Reveal Clues to Limb Regeneration Scientists Coax Brain to Regenerate Cells Lost in Huntington’s Disease Penn Research Shows Way to Improve Stem Cells’ Cartilage Formation Easy and Effective Therapy to Restore Sight: Engineered Virus Will Improve Gene Therapy for Blinding Eye Diseases Cancer Cells' Appetite for Sugar May Have Serious Consequences for Immune Cell Function Mount Sinai Discovers New Liver Cell for Cellular Therapy to Aid in Liver Regeneration Fat Chance: Scientists Unexpectedly Discover Stress-Resistant Stem Cells in Adipose Tissue Reprogrammed Cells a New Tool in Researching Alzheimer's, Schizophrenia, Autism Big Multiple Sclerosis Breakthrough Stem Cells Show Potential to Treat a Leading Cause of Blindness Growth Factor Responsible For Triggering Hair Follicle Generation During Wound Healing Identified, Found in Cells of Short Supply in Humans Researchers Solve Two Longstanding Challenges in Liver Tissue Engineering Enhanced White Blood Cells Heal Mice with MS-Like Disease New Gene Therapy Shows Broad Protection in Animal Models to Pandemic Flu Strains, Including the Deadly 1918 Spanish Influenza Dendritic Cell Therapy Improves Kidney Transplant Survival in Preclinical Model McGowan Institute Military Medicine-Related Research McGowan Institute for Regenerative Medicine Has a Strong Presence at ASAIO Annual Conference NIH Grant to Improve Treatment of Wet Age-Related Macular Degeneration Received Living Donor Kidney Transplants: Increasing the Number of Kidneys Available for Transplantation How Young Genes Gain a Toehold on Becoming Indispensable Biomarker Could Help Scientists Choose the Right Cell Line When Conducting Stem Cell Experiments Gene Therapy Helps Muscular Dystrophy Patients Breathe Easier Researchers Discover How and Where Breast Tumor Cells Become Dormant and What Causes Them to Become Metastatic Researchers Gain Insight Into Key Protein Linked to Cancers, Neurodegenerative Disorders Adult Stem Cells Combined With New Drug Could Hold Key to Curing Type 1 Diabetes Stem Cell Injections Improve Spinal Injuries in Rats Transplantation of Human Stem Cells Improves Muscle Function in Rats Used to Model ALS Survival Rates Increased Among Patients Who Received Blood Stem Cell Transplants: Study Pitt Researchers Find Immune Cells May Play Previously Unrecognized Role in Inflammation in HIV/AIDS Researchers Coax Clays to Make Human Bone Nerve Stimulation Helps with Overactive Bladder Biologists Take Snapshot of Fleeting Protein Process Pitt-led Team Describes Molecular Detail of HIV’s Inner Coat, Pointing the Way to New Therapies Pitt Team Finds Biologic Mechanism That Causes Noise-Induced Tinnitus and Drug That Can Prevent It Modulating the Immune System to Combat Metastatic Cancer New Mechanism for Estrogen Suppression of Liver Lipid Synthesis Study Suggests New Source of Kidneys for Transplant Engineered Biomaterial Could Improve Success of Medical Implants Infantile Myofibromatosis: First Drug Targets in Childhood Genetic Tumor Disorder Biophysicists Measure Mechanism That Determines Fate of Living Cells Protein Preps Cells to Survive Stress of Cancer Growth and Chemotherapy Drug Reverses Alzheimer’s Disease Deficits in Mice, Pitt Research Confirms The Secret Lives (and Deaths) of Neurons Baby's Life Saved With Groundbreaking 3-D Printed Device That Restored His Breathing A Nanotechnology Use for Grapefruits in Improving Drug Delivery Scientists Identify 4 Genes in Baboons That Influence Levels of Bad Cholesterol Breakthrough in the Understanding of How Pancreatic Cancer Cells Ingest Nutrients Points to New Drug Target Stem Cell Researchers Move Toward Treatment For Rare Genetic Nerve Disease Stem-Cell-Based Strategy Boosts Immune System in Mice Brain Rewires Itself After Damage or Injury, Life Scientists Discover Research Breakthrough: Human Skin Cells Become Embryonic Stem Cells Pitt Transplant Experts Challenge Assumption, Describe Biological Pathway That Leads to Organ Rejection Squishy Hydrogels May Be the Ticket for Studying Biological Effects of Nanoparticles Alzheimer's Markers Predict Start of Mental Decline Agent Orange Exposure Linked to Life-Threatening Prostate Cancer Rejuvenating Hormone Found to Reverse Symptoms of Heart Failure Progenitor Cells Remain Highly Dynamic in the Adult Brain Duke Engineers Build Living Patch for Damaged Hearts Etubics Platform Generates Solid Immune Response in Colorectal Cancer Patients One-Two Punch Could Be Key in Treating Blindness DNA-Guided Assembly Yields Novel Ribbon-Like Nanostructures Skin Cancer May Be Linked to Lower Risk of Alzheimer's Disease 'Off-The-Shelf' Virus-Specific T-Cells Fight Viral Infections in Stem Cell Transplant Patients UCLA Stem Cell Researchers Move Toward Treatments For Rare Genetic Nerve Disease Study Finds That Bacteria Organize According to 'Rich-Get-Richer' Principle Study: Bladder Cancer Could Reoccur Despite Bladder Removal Researchers Discover Possible Trigger for Spread of Head and Neck Cancer Cells New Cancer Driver Found Epilepsy Cured in Mice Using Brain Cells NYSCF Scientists Create Personalized Bone Substitutes From Skin Cells Boosting 'Cellular Garbage Disposal' Can Delay the Aging Process, UCLA Biologists Report Divide and Define: Clues to Understanding How Stem Cells Produce Different Kinds of Cells NIH Study Provides Clarity on Supplements for Protection Against Blinding Eye Disease Identification of Stem Cells’ Two Separate Roles Raises Possibility of Therapies That Could Inhibit Fat Formation, Promote Muscle Repair Patterned Hearts New Study Validates Longevity Pathway Discovery Shows Fat Triggers Rheumatoid Arthritis: Paves Way for New Gene Therapies Printable Functional 'Bionic' Ear Melds Electronics and Biology Adult Cells Transformed Into Early-Stage Nerve Cells, Bypassing the Pluripotent Stem Cell Stage Scientists Decode "Molecular Chatter" That Makes Cancer Cells Spread Severe Sports-Related Concussions in Children Prolong Recovery Time Network of Genes Is a Crucial Mechanism Driving Late Onset Alzheimer's Disease Genes Play Role in Wound Healing, Regulate Biological Processes in Human Skin Mild Blast Injury Causes Molecular Changes in Brain Akin to Alzheimer’s Disease, Pitt-Led Team Says UF Researchers Develop ‘Nanotrain’ For Targeted Cancer Drug Transport Battery of Tests on Cancer Cells Shows Them as 'Squishy,' Yet Tactically Strong Pitt Team Finds Melatonin Delays ALS Symptom Onset and Death in Mice Stem Cell Transplant Restores Memory, Learning in Mice A Noninvasive Avenue for Parkinson's Disease Gene Therapy FAP Cells Help in Repairing Injured Muscles Recipe for Making Large Numbers of Stem Cells Requires Only One Ingredient, Says NIH/Pitt Team Outcomes for Treating Heart Failure with Cell Therapy, High-Dose Ultrasound Researchers Morph Ordinary Skin Cells Into Functional Brain Cells Researchers Turn Skin Cells Directly Into the Cells That Insulate Neurons Mass. General Team Develops Implantable, Bioengineered Rat Kidney Lower PSA Predicts Better Survival in Sipuleucel T Recipients Progress Reported in Organ Preservation Adding Breast Milk Ingredient to Formula Could Prevent Deadly Intestinal Problem in Premature Babies Study Finds Late-Life Depression Associated with Increased Risk for Dementia Rigid Growth Matrix: A Key to Success of Cardiac Tissue Engineering Ordinary Skin Cells Morphed Into Functional Brain Cells: New Technique Holds Promise For Multiple Sclerosis Mayo Clinic: Cardiopoietic 'Smart' Stem Cells Show Promise in Heart Failure Patients Stem Cells Boom in Vet Clinics Researchers Engineer 'Protein Switch' to Dissect Role of Cancer's Key Players Moving Cells with Light Holds Medical Promise For the First Time, Researchers Isolate Adult Stem Cells from Human Intestinal Tissue Cholesterol Buildup Links Atherosclerosis and Macular Degeneration Biological Transistor Enables Computing Within Living Cells What Advances are Driving Clinical Applications of Tissue Engineering and Regenerative Medicine? Researchers Decode Biology of Blood and Iron Disorders Mapping Out Novel Future Therapies DOD Highlights Breast Cancer Research of McGowan Institute for Regenerative Medicine Faculty Member Clinical Research Forum Awards Brain Computer Interface Technology Healing by the Clock: In Fruit Flies, Intestinal Stem-Cell Regeneration Fluctuates With the Time of Day New Research Reveals How Autophagy Keeps Neural Stem Cells to Replace Damaged Brain, Nerve Cells Research Shows New Separation Process Could Help Advance Stem Cell Therapies Building Better Blood Vessels Could Advance Tissue Engineering Phase 1 ALS Trial is First to Test Antisense Treatment of Neurodegenerative Disease Protein Is Vital to Successful 'Homing' of Stem Cells, Researchers Discover Pitt Team Finds Protein That Ramps Up Inflammation, and Agents That Can Block It Researchers Are First to Use Common Virus to “Fortify” Adult Stem Cells NYSCF Scientists Develop New Protocol to Ready Clinical Applications of Induced Pluripotent Stem Cells Penn Researchers Show Stem Cell Fate Depends on ‘Grip’ Opposites Attract: How Cells and Cell Fragments Move in Electric Fields ‘Clinical Trials in a Dish’ May be More Reliable Than Standard Way of Measuring Drug Effects on Heart, Researchers Say Stem Cells Entering the Heart Can be Tracked With Nano-‘Hitchhikers,’ Scientists Say Designing Interlocking Building Blocks to Create Complex Tissues Stem Cell Proliferation and Differentiation Observed Within Hydrogel Children’s Hospital of Pittsburgh of UPMC Study Reveals Success Rate of Minimally Invasive Surgical Approaches in Infants Engineered T Cells Kill Tumors but Spare Normal Tissue in an Animal Model Will Cell Therapy Become a 'Third Pillar' of Medicine? New Insights Into How Genes Turn On and Off Gene Therapy May Aid Failing Hearts Pitt, Mount Sinai Team Finds Novel Mechanism Regulating Replication of Insulin-Producing Beta Cells for Diabetes Treatment Monoclonal Antibody Targets, Kills Leukemia Cells New Method Developed to Expand Blood Stem Cells for Bone Marrow Transplant Cell-Based Immune Therapy Shows Promise in Leukemia Patients Counting White Blood Cells at Home Stem Cells Use Signal Orientation to Guide Division, Study Shows Immune-Cell Therapy Could Strengthen Promising Melanoma Treatment Misregulated Genes May Have Big Autism Role Stem Cell Research Could Expand Clinical Use of Regenerative Human Cells Map of 'Shortcuts' Between All Human Genes Fluorescent Neural Cells from Monkey Skin Mature Into Several Types of Brain Cells in Monkeys Immune Cells Cluster and Communicate 'Like Bees,' Researcher Says New Monoclonal Antibody Developed That Can Target Proteins Inside Cancer Cells Protein Abundant in Cancerous Cells Causes DNA 'Supercoiling' Nanoparticles Loaded With Bee Venom Kill HIV Temp-Controlled 'Nanopores' May Allow Detailed Blood Analysis NIH R21 Grant to Develop Adipose Stem-Cell Based Vascular Grafts Received Vision Restoration: Regenerative Medicine in Ophthalmology Edible Electronics Developed for Medical Device Industry Cell Therapy Combo Aids Stroke Backwards Signals Appear to Sensitize Brain Cells, Rat Study Shows Kryptonite for Cancer Cells Depression Stems from Miscommunication Between Brain Cells; Study Challenges Role of Serotonin in Depression Knowing How Brown Fat Cells Develop May Help Fight Obesity Cord Blood Effective Alternative to Matched Donor Stem Cells For Kids With Rare Disorder Stem Cells From Fat Show Promise in Treatment of Brain Cancer New Hope for Reversing the Effects of Spinal Cord Injury BRAF Inhibitor Treatment Causes Melanoma Cells to Shift How They Produce Energy Signaling Molecule May Help Stem Cells Focus on Making Bone Despite Age, Disease Scientists Identify 'Clean-Up' Snafu That Kills Brain Cells in Parkinson's Disease Obesity, Aging Genes May Play Role in Arthritis Genes Identify Breast Cancer Risk and May Aid Prevention Cell on a Chip Reveals Protein Behavior The 3-D Printing of Tomorrow Researchers on Path to Restoring Vision Loss From Diabetic Eye Disease Regulating Cells: Mechanical Forces Play a Major Role in Assembly and Disassembly of a Protein Essential to Many Cell Functions Long-Suspected Cause of Blindness from Eye Disease Disproved Support Cells Found in Human Brain Make Mice Smarter One Region, Two Functions: Brain Cells’ Multitasking May Be a Key to Understanding Overall Brain Function Circuitry of Cells Involved in Immunity, Autoimmune Diseases Exposed Researchers Utilize Genetically Corrected Stem Cells to Spark Muscle Regeneration Obesity Makes Fat Cells Act Like They're Infected Researchers Identify Seven New Genes Associated with Macular Degeneration Wearable Artificial Lung to Be Developed at Pitt Through $3.4 Million Grant First “Breathing Lung” Transplant on East Coast Using OCS Lung Performed Latest Fox Center Research Efforts Children’s Hospital of Pittsburgh of UPMC Study Shows Increase in Liver Transplantation for Hepatoblastoma 2 New Genes Linked to Amyotrophic Lateral Sclerosis and Related Disorders Seven Genetic Risk Factors Found to be Associated with Age-Related Macular Degeneration Reprogramming Adult Cells to Stem Cells Works Better With One Gene Turned Off How Do Bacteria Clog Medical Devices? Very Quickly Study Shows Triple-Negative Breast Cancer Cells Missing Key Enzyme Research Supports Promise of Cell Therapy for Bowel Disease Infusion of Stem Cells and Specially Generated T-Cells from Same Donor Improves Leukemia Survival Swine Cells Could Power Artificial Liver HIF-1α Protein Can Work Directly to Stop New Cells from Forming Bioengineers Print Ears That Look and Act Like the Real Thing Now Hear This: Forerunners of Inner-Ear Cells That Enable Hearing Identified Scientists Find Genes Linked to Human Neurological Disorders in Sea Lamprey Genome OHSU Scientists First to Grow Liver Stem Cells in Culture, Demonstrate Therapeutic Benefit Scientists Find Surprising New Influence on Cancer Genes Distinct Niches in Bone Marrow Nurture Blood Stem Cells Reprogramming Cells to Fight Diabetes UCLA Researchers Further Refine 'NanoVelcro' Device to Grab Single Cancer Cells from Blood Gene Therapy May Activate Stem Cells in Heart Failure Patients New Injectable Hydrogel Encourages Regeneration and Improves Functionality After a Heart Attack Nanotech'ed RNA Drug Reduces Ovarian Cancer Tumors by 83 Percent Bone Marrow Cells Used in Bladder Regeneration Variations in Four Genes Associated With Increased Risk of Colorectal Cancer Fragile X Makes Brain Cells Talk Too Much UCLA Scientists Develop New Therapeutics That Could Accelerate Wound Healing Discovery in HIV May Solve Efficiency Problems for Gene Therapy Protein Central to Cancer Stem Cell Formation Provides New Potential Target Long Noncoding RNAs Control Development of Fat Cells Stem Cell Survival Strategy is Key to Blood and Immune System Health Synthetic Circuit Allows Dialing Gene Expression Up or Down in Human Cells MIT Engineers Create Genetic Circuits in Bacterial Cells Findings Support Link Between Hscrp, Macular Degeneration New Insight Into How Genes Function 'Zombie' Cells May Outperform Live Ones as Catalysts and Conductors Compound Developed by Scientists Protects Heart Cells During and After Attack Investigators Discover Two New Genes Associated With Severe Early-Onset Disorders of Heart Rhythm New Statistical Tool May Help Detect Novel Genes Linked to Heart Disease, Penn Study Reports Tiny Capsule Effectively Kills Cancer Cells Evaluating Evolutionary Rates Could Provide Insight into Functions of Uncharacterized Genes Changes to DNA On-Off Switches Affect Cells' Ability to Repair Breaks, Respond to Chemotherapy Understanding 'Master Regulator' Genes Could Lead to Better Cancer Treatments Immune System Can Use Melanoma's Own Proteins to Kill Off Cancer Cells Growth Factor Aids Stem Cell Regeneration After Radiation Damage How Cancer Cells Rewire Their Metabolism to Survive UIC to Determine Whether Exercise Can Shorten Recovery Time for Stem Cell Transplant Patients Tuberculosis May Lurk in Bone Marrow Stem Cells of Infected Patients Genes Behind Aggressive Endometrial Cancer In Breast Cancer Metastasis, Researchers Identify Possible Drug Target Patients' Own Skin Cells Are Transformed Into Heart Cells to Create 'Disease in a Dish' Monell Scientists Identify Elusive Taste Stem Cells Scientists Learn More About How Inhibitory Brain Cells Get Excited Aging Cells Lose Their Grip on DNA Rogues Better Way to Culture Central Nervous Cells Study Shows Potential of Differentiated iPS Cells in Cell Therapy Without Immune Rejection Study Eyes Stem Cell Blood Test to Detect Macular Degeneration Progression Tumor Cells Engineer Acidity to Drive Cell Invasion New Method Identifies Genes That Can Predict Prognoses of Cancer Patients Cardiac Development Needs More Than Protein-Coding Genes Stem Cell Therapy to Repair Damaged Knee Cartilage Stem Cell Research Helps to Identify Origins of Schizophrenia How Cells' DNA Repair Machinery Can Destroy Viruses Light Shed on Complexity of Gene Therapy for Congenital Blindness Immune Cells Engineered in Lab to Resist HIV Infection, Stanford Study Shows Enzyme Helps Cancer Cells Avoid Genetic Instability Epigenetics Explains Rheumatism? Genes and Their Regulatory 'Tags' Conspire to Promote Rheumatoid Arthritis Stage IV Cancer Cells Even More Susceptible to Grape Seed Extract than Stage II Low Blood Flow to the Premature Brain Disrupts Cells' Ability to Fully Mature Human Hearts Generate New Cells After Birth; Findings Could Lead to Novel Approaches For Treating Heart Failure in Children How Cells Know When It's Time to Eat Themselves Drug Targets Hard-to-Reach Leukemia Stem Cells Responsible For Relapses A Quantum Leap in Gene Therapy of Duchenne Muscular Dystrophy Discovery That Some Seizures Arise in Glial Cells Could Offer New Targets For Epilepsy Treatment Stem-Cell Approach Shows Promise For Duchenne Muscular Dystrophy Rice-Cell Cocktail Kills Cancer Cells, Leaves Normal Cells Alone Next Steps in Potential Stem Cell Therapy For Diabetes: Study Looks at Differentiation of hESCs in Endocrine Cell Progression Multiple Sclerosis Study Reveals How Killer T Cells Learn to Recognize Nerve Fiber Insulators Genetic Form of Anemia Offers New Avenue to Treating Drug-Resistant Tumors Why Do Age-Related Macular Degeneration Patients Have Trouble Recognizing Faces? McGowan Institute for Regenerative Medicine Holds Its Annual Scientific Retreat Regenerative Medicine Clinical Translation McGowan Institute for Regenerative Medicine Affiliated Faculty Member Studies Cerebral Aneurysms Mechanism to Halt Cancer Cell Growth, Discover Potential Cancer Therapy Revealed UCSD Team Invents Brain Cell Breakthrough Sickle Cells Show Potential to Attack Aggressive Cancer Tumors Sensory Hair Cells Regenerated, Hearing Restored in Noise-Damaged Mammal Ear Chemists Devise Inexpensive, Benchtop Method for Marking and Selecting Cells Genes and Obesity: Fast Food Isn't Only Culprit in Expanding Waistlines -- DNA Is Also to Blame Pitt Vaccine Triggers Immunity to Prevent Colon Cancer Cheap and Easy Technique to Snip DNA Could Revolutionize Gene Therapy Pitt Enzyme Discovery May Lead to Better Tests for Tuberculosis Gene Therapy Reprograms Scar Tissue in Damaged Hearts into Healthy Heart Muscle Sorting Stem Cells Children’s Hospital/Pitt-Led Team Finds Molecule That Polices TB Lung Infection, Could Lead to Effective Vaccine Itchiness Explained: Specific Set of Nerve Cells Signal Itch But Not Pain, Researchers Find Scientists Unlock How Insulin Interacts With Cells Rare Form of Active 'Jumping Genes' Found in Mammals Risk Genes for Alzheimer's and Mental Illness Linked to Brain Changes at Birth First Ever 'Atlas' of T Cells in Human Body 2 Novel Treatments for Retinitis Pigmentosa Move Closer to Clinical Trials Low Vitamin D Levels Early in Pregnancy Associated With Lower Birth Weights, Pitt Research Finds Transplanted Neural Stem Cells Treat Amyotrophic Lateral Sclerosis in Mouse Model 'Two-Faced' Cells Discovered in Colon Cancer Brain Cells Activated, Reactivated in Learning and Memory Strange Behavior: New Study Exposes Living Cells to Synthetic Protein Study Hints That Stem Cells Prepare For Maturity Much Earlier Than Anticipated Removing Protein 'Garbage' in Nerve Cells May Help Control 2 Neurodegenerative Diseases Rebuilding Blood Vessels Through Gene Therapy Steering Stem Cells to Become Two Different Building Blocks for New Blood Vessels Protein Regulates Protein Folding in Cells During Stress How Airway Cells Regenerate After Chlorine Gas Injury Gene Therapy Cocktail Shows Promise in Long-Term Clinical Trial for Rare Fatal Brain Disorder Cancer Cells Co-Opt Immune Response to Escape Destruction Protein Creates Paths for Growing Nerve Cells How Hepatitis C Virus Reprograms Human Liver Cells Spread of Cancer Cells May Be Slowed by Targeting of Protein New Technique Could Make Cell-Based Immune Therapies for Cancer Safer and More Effective Ordinary Heart Cells Become 'Biological Pacemakers' With Injection of a Single Gene Tissue Engineering -- Growing New Organs and More: Research Could Lead to Better Ways to Heal Injuries and Develop New Drugs Pitt Cancer Institute Finds New Targets for Drugs to Defeat Aggressive Brain Tumor Pre-Transplant Umbilical Cord Blood Expansion in Lab Speeds Establishment of New Blood Supply in Patients, Reducing High-Risk Time to Recovery Capturing Circulating Cancer Cells Could Provide Insights into How Disease Spreads Joslin Scientists Find That Brown Adipose Tissue Has Beneficial Effects on Metabolism and Glucose Tolerance Fragile X Protein Linked to Nearly 100 Genes Involved in Autism Blocking Myeloid-Derived Suppressor Cells after Lymphopenia Improves Adoptive T-Cell Therapy Steroid Hormone Receptor Prefers Working Alone to Shut Off Immune System Genes Carbon Nanotubes Lower Nerve-Damaging Chloride in Cells Plastics Used in Some Medical Devices Break Down in a Previously Unrecognized Way Studying Marrow, Researchers Accelerate Blood Stem Cells Multitasking Plasmonic Nanobubbles Kill Diseased Cells, Modify Others Mitral Valve Repair Safe and Effective for Elderly Patients Once Considered Too High Risk Based on Age Alone Precisely Engineering 3-D Brain Tissues Arrowhead Publishes First Ever Cholesterol-SiRNA Mediated Gene Knockdown in Primates and Novel DPC Co-Injection Strategy Study Advances Use of Stem Cells in Personalized Medicine “Different Kind of Stem Cell” Possesses Attributes Favoring Regenerative Medicine Intestinal Immune Cells Play an Unexpected Role in Immune Surveillance of the Bloodstream Regenerative Medicine Technology Meets Funding Milestone Study: Biomarkers May Predict Acute Kidney Injury in Critically Ill Patients First International VAD Guidelines Co-Authored by McGowan Institute for Regenerative Medicine Affiliated Faculty Member Stem Cells Found to Heal Damaged Artery in Pre-Clinical Lab Study Advances in Ophthalmology Oscillating Gel Gives Synthetic Materials the Ability to “Speak” Advances in Stem Cell Research Techniques and New Transplant Strategies Reveal Opportunities for Improved Patient Outcomes with Reduced Risk of Complications Genes That Predict Whether Trastuzumab Will Work for Breast Cancer Patients Identified Study: Fasting May Benefit Patients With Epilepsy 5 Big Strides to Fight Lung Disease in Our Tiniest Patients Biomedical Technology Research Center Established Watch Out For Sjögren's Syndrome in Dry Eye From Degeneration to Regeneration: Advances in Skeletal Muscle Engineering Transposable Elements Reveal a Stem Cell Specific Class of Long Noncoding RNAs Researchers Link New Molecular Culprit to Breast Cancer Progression McGowan Institute for Regenerative Medicine-Developed Technology: Study Utilizing HeartMate II® Receives FDA Nod Study Identifies Reasons to Opt Out of Bone-Marrow Donor Registries Breakthrough: Restoration of Function Using BCI Technology and Training Programs Stimulating Brain and Nerves at Synchronized Times Improves Hand Motor Function After Incomplete Spinal Cord Injury Pitt Research Sheds New Light on Virus Associated With Developmental Delays and Deafness; Offers Hope for Treatment Cartilage Made Easy With Novel Hybrid Printer Researchers Identify Protein Key in Proliferation of Lymphoma Cells Engineering a Photo-Switch For Nerve Cells in the Eye and Brain New Study Decodes Molecular Mechanisms Underlying Stem Cell Reprogramming How Cells in the Nose Detect Odors Scientists Develop Single-Cell Imaging to Watch the Cell Clock New Type of Bacterial Protection Found Within Cells Wyss Institute Models a Human Disease in an Organ-on-a-Chip Stem Cells + Nanofibers = Promising Nerve Research Discovery of New Type of RNA Could Have Implications for Some Congenital Disorders Highlights from the Second Annual Symposium on Regenerative Rehabilitation MicroRNAs Can Convert Normal Cells into Cancer Promoters 'Different Kind of Stem Cell' Possesses Attributes Favoring Regenerative Medicine Body May Be Able to 'Coach' Transplanted Stem Cells to Differentiate Appropriately Neurons Made from Stem Cells Drive Brain Activity After Transplantation in Laboratory Model Some Cells Don’t Know When to Stop Pancreas Stem Cell Discovery May Lead to New Diabetes Treatments Injectable Sponge Delivers Drugs, Cells, and Structure Cells from Skin Create Model of Blinding Eye Disease Fat-Derived Stem Cells Hold Potential for Regenerative Medicine Recently Discovered Stem Cell Population Could One Day Provide Useful Source Material for Kidney Repair Researchers Create New Stem Cell-Derived Cell Type for Treatment of Alzheimer's Team Uses Antisense Technology That Exploits Gene Splicing Mechanism to Kill Cancer Cells Stem Cells Could Heal Equine Tendon Injuries Microscopic Packets of Stem Cell Factors Could be Key to Preventing Lung Disease in Babies Duke Researchers Engineer Cartilage from Pluripotent Stem Cells Researchers Identify Novel Genes That May Drive Rare, Aggressive Form of Uterine Cancer Genetic Tradeoff: Harmful Genes Are Widespread in Yeast but Hold Hidden Benefits Pitt Team Receives $5.4 Million in DOD Grants for High-Definition Scans of Soldiers with Brain Injuries Genetic Link Between Pancreatitis and Alcohol Consumption Modeling Tissue Engineered Constructs Solving Stem Cell Mysteries Omega-3 Intake Heightens Working Memory in Healthy Young Adults Mouse Model Could Help Identify Viral Vectors That May Cause Tumors Researchers at the Doorstep of Stem Cell Therapies for MS, Other Myelin Disorders New Anti-Tumor Cell Therapy Strategies Are More Effective Researchers Test New Gene Therapy Method in Human Cells Breast Cancer Cells Enticed to Spread by 'Tumorous Environment' as Well as Genetic Changes Bacterial Genes Energy-Sensing Switch Discovery Could Have Broad Implications New Study Shows Reprogrammed Amniotic Fluid Cells Could Treat Vascular Diseases Peripheral Blood Stem Cell Transplants from Unrelated Donors Associated with Higher Rates of Chronic Graft-Versus-Host-Disease Researchers Study ACT TIL Approach to Treating Metastatic Melanoma First-of-its-Kind Self-Assembled Nanoparticle for Targeted and Triggered Thermo-Chemotherapy New Technique for Sorting Live Cells May Expedite Biomedical Research Calcium Reveals Connections Between Neurons Leading Bone Marrow Transplant Expert Recommends Significant Change to Current Practice Stem Cell Model for Hereditary Disease Developed UCLA Engineers Control Thousands of Cells Simultaneously Using Magnetic Nanoparticles Rare Cells Regulate Immune Responses; May Offer Novel Treatment for Autoimmune Diseases Human Neural Stem Cells Study Offers New Hope for Children with Fatal Brain Diseases Chaperone Protein Subverts Removal of Glaucoma-Causing Protein First Use in Patient of Conditionally Reprogrammed Cells Delivers Clinical Response A Complex Logic Circuit Made From Bacterial Genes How Cancer Cells Break Free From Tumors Stem Cells Form Human Bone Study Suggests Stem Cell Transplant Survivors at Increased Risk of Developing Heart Disease Mayo Clinic Finds Way to Weed Out Problem Stem Cells, Making Therapy Safer Deadly Complication of Stem Cell Transplants Reduced in Mice Researchers Develop Cranial Neural Crest Cell Lines The Cost of Glaucoma Care: Small Group of Patients Accounts for Large Part of Costs Discovery of Essential Genes for Drug-Resistant Bacteria Reveals New, High-Value Drug Targets Tracking Stem Cell Reprogramming Lab Study Suggests That Male Fertility Can Be Restored After Cancer Treatment Seed Funds Help Make NIH Funding Possible Project Awarded Funding: Targeted Molecular Therapeutics for Head and Neck Cancer Researchers Find Multiple Similarities Between Cancer Cells and Induced Pluripotent Stem Cells Study Examines How to Control Spatial Distribution of Cells in Microenvironments Making it Easier to Make Stem Cells First-Ever Imaging of Cells Growing on Spherical Surfaces Discovery of Reprogramming Signature May Help Overcome Barriers to Stem Cell-Based Regenerative Medicine New Stem Cell Differentiation Study Could Help Scientists Better Understand Genetic Basis of CVD Neural Stem Cells Regenerate Axons in Severe Spinal Cord Injury Study Finds That Natural Killer T-Cells in Fat Tissue Guard Against Obesity Gene Linking Cataracts and Alzheimer's Disease Identified Fasting Makes Brain Tumors More Vulnerable to Radiation Therapy Improved Nanoparticles Deliver Drugs into Brain Researchers Restore Children's Immune Systems with Refinements in Gene Therapy Beacons Light Up Stem Cell Transformation Study Suggests Neonatal Cardiac Stem Cells May Help Mend Children's Broken Hearts Computer Simulations Could Lead to Better Cardiac Pump for Children with Heart Defects Hearing Impaired Ears Hear Differently in Noisy Environments One Step Closer to Understanding Actions of Cells Involved in Atherosclerosis Imaging Metals Within Cells: Identifying The Proteins That Bind Stem Cells Show Promise in Halting Heart Attack’s Ripple Effect Genome Wide Scan Maps Mutations in Deadly Lung Cancers Stanford Researchers Create Tiny, Wirelessly Powered Cardiac Device Regenerative Medicine in Vision Research ACL Reconstruction: 4 Points from Dr. Freddie F