Authors:
Danielle Rand, Vivian Ortiz, Yanan Liu, Zoltan Derdak, Jack R. Wands, Milan Tatiček, and Christoph Rose-Petruck
Summary:
We present the development of a new imaging technique for the early diagnosis of hepatocellular carcinoma that utilizes surface-modified gold nanoparticles in combination with X-ray imaging. Tissues labeled with these electron-dense particles show enhanced X-ray scattering over normal tissues, distinguishing cells containing gold nanoparticles from cells without gold in X-ray scatter images. Our results suggest that this novel approach could enable the in vivo detection of tumors as small as a few millimeters in size.
Source:
NANO Letters; 11(7), 2678-2683 (06/06/11)