KPC and NDM-1 genes in related Enterobacteriaceae strains and plasmids from Pakistan and the United States
Authors:
Mitchell W. Pesesky, Tahir Hussain, Meghan Wallace, Bin Wang, Saadia Andleeb, Carey-Ann D. Burnham, and Gautam Dantas
Summary:
To characterize the genomic context of New Delhi metallo-β-lactamase-1 (NDM-1) and Klebsiella pneumoniae carbapenemase (KPC), we sequenced 78 Enterobacteriaceae isolates from Pakistan and the United States encoding KPC, NDM-1, or no carbapenemase. High similarities of the results indicate rapid spread of carbapenem resistance between strains, including globally disseminated pathogens.
Source: Emerging Infectious Diseases; Vol. 21, No. 6 (06/2015)
Summary:
To characterize the genomic context of New Delhi metallo-β-lactamase-1 (NDM-1) and Klebsiella pneumoniae carbapenemase (KPC), we sequenced 78 Enterobacteriaceae isolates from Pakistan and the United States encoding KPC, NDM-1, or no carbapenemase. High similarities of the results indicate rapid spread of carbapenem resistance between strains, including globally disseminated pathogens.
Source: Emerging Infectious Diseases; Vol. 21, No. 6 (06/2015)