Authors:
Miriam Avadisian, Dr. Steven Fletcher, Baoxu Liu, Dr. Wei Zhao, Dr. Peibin Yue, Daniel Badali, Dr. Wei Xu, Dr. Aaron D. Schimmer, Prof. Dr. James Turkson, Prof. Dr. Claudiu C. Gradinaru, & Prof. Dr. Patrick T. Gunning
Summary:
Keeping harm at bay: In an in vitro strategy to prevent the cellular motility of oncogenic STAT3 protein, protein–membrane anchorage was induced by the use of a rationally designed cholesterol-based protein–membrane anchor in breast-tumor cells. (The fluorescence image shows the localization of the protein to the liposome boundary of a multilamellar vesicle.)
Source:
Angewandte Chemie; Vol. 50, Issue 28, 6248-6253 (07/04/11)