Authors:
Yingjie Peng, Dae Hee Kim, Teresa M. Jones, Diana I. Ruiz, & Richard A. Lerner
Summary:
Vectors have been constructed that express the chitin-binding domain (ChBD) on eukaryotic cell surfaces. The ChBD is linked to enhanced green fluorescent protein (EGFP) through a protein that spans the plasma membrane (see picture). This binding functionality does not have a counterpart in eukaryotes, thereby endowing the modified cell surface with a property that is orthogonal to animal cells.
Source:
Angewandte Chemie International Edition; Vol. 52, Issue 1, 336-340 (01/02/13)